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Literature summary extracted from
- Proteus mirabilis urease: histidine 320 of UreC is essential for urea hydrolysis and nickel ion binding within the native enzyme (1993), Infect. Immun., 61, 2570-2577.
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.5.1.5 | Nickel | His320 of subunit C is essential for urea hydrolysis and Ni2+ binding within the native enzyme | Proteus mirabilis |  |
| 3.5.1.5 | Nickel | nickel metalloenzyme | Proteus mirabilis | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.1.5 | urea + H2O | Proteus mirabilis | urease is a critical virulence factor in urinary tract infection | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.1.5 | Proteus mirabilis | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.1.5 | urea + H2O | - |
Proteus mirabilis | CO2 + NH3 | - |
? | |
| 3.5.1.5 | urea + H2O | urease is a critical virulence factor in urinary tract infection | Proteus mirabilis | ? | - |
? | |
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