Literature summary extracted from

Houimel, M.; Mach, J.P.; Corthesy-Theulaz, I.; Fisch, I.
New inhibitors of Helicobacter pylori urease holoenzyme selected from phage-displayed peptide libraries (1999), Eur. J. Biochem., 262, 774-780.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.5.1.5	peptides	TFLPQPRCSALLRYLSEDGVIVPS and YDFYWW, no inhibition of the enzyme from Bacillus pasteurii and Canavalia ensiformis	Helicobacter pylori

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.5.1.5	urea + H2O	Helicobacter pylori	important virulence factor	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.5.1.5	Canavalia ensiformis	-	-	-
3.5.1.5	Helicobacter pylori	-	-	-
3.5.1.5	Sporosarcina pasteurii	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.5.1.5	urea + H2O	-	Helicobacter pylori	CO2 + NH3	-	?
3.5.1.5	urea + H2O	-	Canavalia ensiformis	CO2 + NH3	-	?
3.5.1.5	urea + H2O	-	Sporosarcina pasteurii	CO2 + NH3	-	?
3.5.1.5	urea + H2O	important virulence factor	Helicobacter pylori	?	-	?

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Release 2023.1 (January 2023)