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Literature summary extracted from

  • Hillyard, D.; Rechsteiner, M.; Manlapaz-Ramos, P.; Imperial, J.S.; Cruz, L.J.; Olivera, B.M.
    The pyridine nucleotide cycle. Studies in Escherichia coli and the human cell line D98/AH2 (1981), J. Biol. Chem., 256, 8491-8497.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.1.42 0.014
-
beta-nicotinamide D-ribonucleotide
-
Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.5.1.42 intracellular
-
Escherichia coli 5622
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.1.42 beta-nicotinamide D-ribonucleotide + H2O Escherichia coli contribution to the recycling pathway of NAD+ beta-nicotinate D-ribonucleotide + NH3
-
?
3.5.1.42 beta-nicotinamide D-ribonucleotide + H2O Homo sapiens contribution to the recycling pathway of NAD+ beta-nicotinate D-ribonucleotide + NH3
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.42 Escherichia coli
-
-
-
3.5.1.42 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.1.42 near homogeneity, chromatography techniques Escherichia coli

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.42 cell culture
-
Escherichia coli
-
3.5.1.42 cell culture
-
Homo sapiens
-
3.5.1.42 HeLa cell
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.5.1.42 2900
-
-
Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.42 beta-nicotinamide D-ribonucleotide + H2O
-
Escherichia coli beta-nicotinate D-ribonucleotide + NH3
-
?
3.5.1.42 beta-nicotinamide D-ribonucleotide + H2O
-
Homo sapiens beta-nicotinate D-ribonucleotide + NH3
-
?
3.5.1.42 beta-nicotinamide D-ribonucleotide + H2O contribution to the recycling pathway of NAD+ Escherichia coli beta-nicotinate D-ribonucleotide + NH3
-
?
3.5.1.42 beta-nicotinamide D-ribonucleotide + H2O contribution to the recycling pathway of NAD+ Homo sapiens beta-nicotinate D-ribonucleotide + NH3
-
?

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.5.1.42 5
-
no activity below Escherichia coli