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Literature summary extracted from

  • Chen, P.R.S.; Dauterman, W.C.
    Alkylamidase of sheep liver (1971), Biochim. Biophys. Acta, 250, 216-223.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.39 O,O-diethyl p-nitrophenyl phosphate inhibition at 0.001 mM Ovis aries aries
3.5.1.39 p-chloromercuribenzoate 20% inhibition at 1 mM Ovis aries aries

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.1.39 0.19
-
 N,N-dimethylcaproamide inhibition by excess of substrate Ovis aries aries
3.5.1.39 0.66
-
 N-methylcaproamide inhibition by excess of substrate Ovis aries aries
3.5.1.39 0.83
-
 N-ethylcaproamide inhibition by excess of substrate Ovis aries aries
3.5.1.39 1.25
-
 N-methylheptylamide inhibition by excess of substrate Ovis aries aries
3.5.1.39 1.8
-
 N-propylcaproamide inhibition by excess of substrate Ovis aries aries
3.5.1.39 2.2
-
 N-Butylcaproamide inhibition by excess of substrate Ovis aries aries
3.5.1.39 2.5
-
 N-phenylcaproamide inhibition by excess of substrate Ovis aries aries
3.5.1.39 3.7
-
 N-methylcaprylamide inhibition by excess of substrate Ovis aries aries
3.5.1.39 5
-
 N-methylvaleramide inhibition by excess of substrate Ovis aries aries

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.5.1.39 microsome
-
 Ovis aries aries
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.5.1.39 230000 250000 gel filtration Ovis aries aries

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.39 Ovis aries aries
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.1.39 to homogeneity, 2step chromatography Ovis aries aries

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.39 liver
-
 Ovis aries aries
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.5.1.39 0.12
-
-
 Ovis aries aries

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.39 N,N-dimethylcaproamide + H2O
-
 Ovis aries aries dimethylamine + hexanoate
-
 ?
3.5.1.39 N-butylcaproamide + H2O
-
 Ovis aries aries butylamine + hexanoate
-
 ?
3.5.1.39 N-ethylcaproamide + H2O
-
 Ovis aries aries ethylamine + hexanoate
-
 ?
3.5.1.39 N-methylbutyramide + H2O
-
 Ovis aries aries methylamine + butyric acid
-
 ?
3.5.1.39 N-methylcaproamide + H2O
-
 Ovis aries aries methylamine + hexanoate
-
 ?
3.5.1.39 N-methylcaprylamide + H2O low activity Ovis aries aries methylamine + octanoate
-
 ?
3.5.1.39 N-methylheptylamide + H2O
-
 Ovis aries aries methylamine + heptanoate
-
 ?
3.5.1.39 N-methylvaleramide + H2O unable to hydrolyze lower members of N-methyl substituted amides Ovis aries aries methylamine + pentanoate
-
 ?
3.5.1.39 N-phenylcaproamide + H2O
-
 Ovis aries aries phenylamine + hexanoate
-
 ?
3.5.1.39 N-propylcaproamide + H2O
-
 Ovis aries aries propylamine + hexanoate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.1.39 9
-
-
 Ovis aries aries