Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Hersh, L.B.
    The effect of aliphatic alcohols and organic solvents on methylpyroglutamate synthetase (1971), J. Biol. Chem., 246, 7804-7809.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.5.1.36 acetone noncompetitive activator with respect to ethanolamine Pseudomonas sp.
3.5.1.36 aliphatic alcohols 7fold increase of hydrolysis of alpha-ketoglutaramate and ethyl alpha-ketoglutarate Pseudomonas sp.
3.5.1.36 Dimethyl formamide noncompetitive activator with respect to ethanolamine Pseudomonas sp.
3.5.1.36 dioxane noncompetitive activator, effect on the reaction of methylamine with ethyl alpha-ketoglutarate Pseudomonas sp.
3.5.1.36 organic solvents increase both hydrolysis and transfer reactions involving amines, accelerated up to 7fold Pseudomonas sp.

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.36 aliphatic alcohols with respect to amines in acyl transfer reactions Pseudomonas sp.
3.5.1.36 butanol competitive inhibitors with respect to methylamine and ethanolamine Pseudomonas sp.
3.5.1.36 Pentanol competitive to ethanolamine Pseudomonas sp.
3.5.1.36 Propanol competitive to ethanoamine Pseudomonas sp.

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.36 Pseudomonas sp.
-
-
-
3.5.1.36 Pseudomonas sp. MA / M.A. / ATCC 23819
-
-
-