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Literature summary extracted from

  • Hsu, L.L.; Halaris, A.E.; Freedman, D.X.
    Rat brain aryl acylamidase: further characterization of multiple forms (1982), Int. J. Biochem., 14, 581-584.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.5.1.13 6-methoxy-harmalan enhances activity of enzyme form AAA-1 and AAA-2 Rattus norvegicus
3.5.1.13 6-methoxy-harman enhances activity of enzyme form AAA-1 and AAA-2 Rattus norvegicus
3.5.1.13 chlorimipramine stimulates enzyme form AAA-2 Rattus norvegicus
3.5.1.13 cyproheptadine stimulates enzyme form AAA-2 Rattus norvegicus
3.5.1.13 Harmaline enhances activity of enzyme form AAA-1 and AAA-2 Rattus norvegicus
3.5.1.13 harmalol enhances activity of enzyme form of AAA-2 Rattus norvegicus
3.5.1.13 methiothepin stimulates enzyme form AAA-2 Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.13 1,2,3,4-tetrahydro-beta-carboline competitive inhibition of AAA-1, slight inhibition of enzyme form AAA-2 Rattus norvegicus
3.5.1.13 6-hydroxy-tetrahydroharman slight inhibition of enzyme form AAA-1 and AAA-2 Rattus norvegicus
3.5.1.13 chlorimipramine enzyme form AAA-1 Rattus norvegicus
3.5.1.13 cyproheptadine enzyme form AAA-1 Rattus norvegicus
3.5.1.13 harmalol enzyme form of AAA-1 Rattus norvegicus
3.5.1.13 harminic acid slight inhibition of enzyme form AAA-1 and AAA-2 Rattus norvegicus
3.5.1.13 methiothepin enzyme form AAA-1 Rattus norvegicus
3.5.1.13 neostigmine inhibition of enzyme form AAA-2, no effect of enzyme form AAA-1 Rattus norvegicus
3.5.1.13 tetrahydroharman
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.13 Rattus norvegicus
-
 enzyme form AAA-1 and AAA-2
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.13 brain
-
 Rattus norvegicus
-