Literature summary extracted from

Kyriakidis, D.A.; Tsirka, S.A.E.; Tsavdaridis, I.K.; Iliadis, S.N.; Kortsaris, A.H.
Antiproliferative activity of L-asparaginase of Tetrahymena pyriformis on human breast cancer cell lines (1990), Mol. Cell. Biochem., 96, 137-142.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.5.1.1	D-Asn	competitive, reverses antiproliferating effect on breast cancer cells	Tetrahymena pyriformis

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.5.1.1	Tetrahymena pyriformis	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.5.1.1	L-Asn + H2O	-	Tetrahymena pyriformis	L-Asp + NH3	-	?
3.5.1.1	additional information	antiproliferating activity on the breast cancer cell lines T47D, BT20, and MCF-7	Tetrahymena pyriformis	?	-	?
3.5.1.1	additional information	protein kinase activity	Tetrahymena pyriformis	?	-	?

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Release 2023.1 (January 2023)