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Literature summary extracted from
- Epoxide hydratase (1979), Prog. Drug Metab., 3, 253-301.
No PubMed abstract available
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.3.2.9 | microsome | - |
Cavia porcellus | - |
- |
| 3.3.2.9 | microsome | - |
Mus musculus | - |
- |
| 3.3.2.9 | microsome | - |
Rattus norvegicus | - |
- |
| 3.3.2.9 | microsome | - |
Oryctolagus cuniculus | - |
- |
| 3.3.2.9 | microsome | - |
Felis catus | - |
- |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.3.2.9 | 49000 | - |
x * 49000, SDS-PAGE | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.3.2.9 | additional information | Cavia porcellus | - |
? | - |
? |  |
| 3.3.2.9 | additional information | Mus musculus | - |
? | - |
? | |
| 3.3.2.9 | additional information | Rattus norvegicus | potent and selective induction by trans-stilbene oxide | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.3.2.9 | Cavia porcellus | - |
- |
- |
| 3.3.2.9 | Felis catus | - |
- |
- |
| 3.3.2.9 | Mus musculus | - |
- |
- |
| 3.3.2.9 | Oryctolagus cuniculus | - |
- |
- |
| 3.3.2.9 | Pigeon | - |
- |
- |
| 3.3.2.9 | quail | - |
- |
- |
| 3.3.2.9 | Rattus norvegicus | - |
- |
- |
| 3.3.2.9 | Sus scrofa | - |
- |
- |
| 3.3.2.9 | toad | - |
- |
- |
| 3.3.2.9 | trout | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.3.2.9 | - |
Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.3.2.9 | adrenal gland | - |
Cavia porcellus | - |
| 3.3.2.9 | adrenal gland | - |
Rattus norvegicus | - |
| 3.3.2.9 | bladder | - |
Rattus norvegicus | - |
| 3.3.2.9 | brain | - |
Cavia porcellus | - |
| 3.3.2.9 | brain | - |
Rattus norvegicus | - |
| 3.3.2.9 | cecum | - |
Rattus norvegicus | - |
| 3.3.2.9 | colon | - |
Rattus norvegicus | - |
| 3.3.2.9 | dermis | - |
Rattus norvegicus | - |
| 3.3.2.9 | epidermis | - |
Rattus norvegicus | - |
| 3.3.2.9 | esophagus | - |
Rattus norvegicus | - |
| 3.3.2.9 | heart | - |
Rattus norvegicus | - |
| 3.3.2.9 | liver | - |
Cavia porcellus | - |
| 3.3.2.9 | liver | - |
Mus musculus | - |
| 3.3.2.9 | liver | - |
Rattus norvegicus | - |
| 3.3.2.9 | liver | - |
Oryctolagus cuniculus | - |
| 3.3.2.9 | lung | - |
Rattus norvegicus | - |
| 3.3.2.9 | lung | - |
Oryctolagus cuniculus | - |
| 3.3.2.9 | muscle | triceps | Rattus norvegicus | - |
| 3.3.2.9 | ovary | - |
Rattus norvegicus | - |
| 3.3.2.9 | prostate gland | - |
Rattus norvegicus | - |
| 3.3.2.9 | small intestine | - |
Cavia porcellus | - |
| 3.3.2.9 | small intestine | - |
Rattus norvegicus | - |
| 3.3.2.9 | spleen | - |
Rattus norvegicus | - |
| 3.3.2.9 | stomach | membranous and glandular | Rattus norvegicus | - |
| 3.3.2.9 | subcutis | - |
Rattus norvegicus | - |
| 3.3.2.9 | submandibular gland | - |
Rattus norvegicus | - |
| 3.3.2.9 | testis | - |
Mus musculus | - |
| 3.3.2.9 | testis | - |
Rattus norvegicus | - |
| 3.3.2.9 | testis | - |
Oryctolagus cuniculus | - |
| 3.3.2.9 | thymus | - |
Rattus norvegicus | - |
| 3.3.2.9 | tongue | - |
Rattus norvegicus | - |
| 3.3.2.9 | trachea | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.3.2.9 | additional information | - |
- |
Mus musculus |
| 3.3.2.9 | additional information | - |
- |
Rattus norvegicus |
| 3.3.2.9 | additional information | - |
- |
Oryctolagus cuniculus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.3.2.9 | 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O | - |
Cavia porcellus | ? | - |
? | |
| 3.3.2.9 | 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O | - |
Mus musculus | ? | - |
? | |
| 3.3.2.9 | 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 3.3.2.9 | 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O | - |
Sus scrofa | ? | - |
? | |
| 3.3.2.9 | 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
| 3.3.2.9 | 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O | - |
Pigeon | ? | - |
? | |
| 3.3.2.9 | 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O | - |
Felis catus | ? | - |
? | |
| 3.3.2.9 | 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O | - |
toad | ? | - |
? | |
| 3.3.2.9 | 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O | - |
trout | ? | - |
? | |
| 3.3.2.9 | 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O | - |
quail | ? | - |
? | |
| 3.3.2.9 | benzopyrene 4,5-oxide + H2O | - |
Cavia porcellus | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| 3.3.2.9 | benzopyrene 4,5-oxide + H2O | - |
Mus musculus | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| 3.3.2.9 | benzopyrene 4,5-oxide + H2O | - |
Rattus norvegicus | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| 3.3.2.9 | benzopyrene 4,5-oxide + H2O | - |
Sus scrofa | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| 3.3.2.9 | benzopyrene 4,5-oxide + H2O | - |
Oryctolagus cuniculus | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| 3.3.2.9 | benzopyrene 4,5-oxide + H2O | - |
Pigeon | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| 3.3.2.9 | benzopyrene 4,5-oxide + H2O | - |
Felis catus | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| 3.3.2.9 | benzopyrene 4,5-oxide + H2O | - |
toad | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| 3.3.2.9 | benzopyrene 4,5-oxide + H2O | - |
trout | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| 3.3.2.9 | benzopyrene 4,5-oxide + H2O | - |
quail | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| 3.3.2.9 | additional information | - |
Cavia porcellus | ? | - |
? | |
| 3.3.2.9 | additional information | - |
Mus musculus | ? | - |
? | |
| 3.3.2.9 | additional information | potent and selective induction by trans-stilbene oxide | Rattus norvegicus | ? | - |
? | |
| 3.3.2.9 | styrene oxide + H2O | - |
Cavia porcellus | styrene glycol | - |
? | |
| 3.3.2.9 | styrene oxide + H2O | - |
Mus musculus | styrene glycol | - |
? | |
| 3.3.2.9 | styrene oxide + H2O | - |
Rattus norvegicus | styrene glycol | - |
? | |
| 3.3.2.9 | styrene oxide + H2O | - |
Sus scrofa | styrene glycol | - |
? | |
| 3.3.2.9 | styrene oxide + H2O | - |
Oryctolagus cuniculus | styrene glycol | - |
? | |
| 3.3.2.9 | styrene oxide + H2O | - |
Pigeon | styrene glycol | - |
? | |
| 3.3.2.9 | styrene oxide + H2O | - |
Felis catus | styrene glycol | - |
? | |
| 3.3.2.9 | styrene oxide + H2O | - |
toad | styrene glycol | - |
? | |
| 3.3.2.9 | styrene oxide + H2O | - |
trout | styrene glycol | - |
? | |
| 3.3.2.9 | styrene oxide + H2O | - |
quail | styrene glycol | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.3.2.9 | ? | - |
Cavia porcellus |
| 3.3.2.9 | ? | - |
Mus musculus |
| 3.3.2.9 | ? | x * 49000, SDS-PAGE | Rattus norvegicus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.3.2.9 | 7.4 | - |
hydration of benzopyrene 4,5-oxide | Rattus norvegicus |
| 3.3.2.9 | 8.9 | - |
hydration of styrene oxide, Tris buffer | Rattus norvegicus |
| 3.3.2.9 | 8.9 | - |
hydration of benzopyrene 7,8-oxide and benzopyrene 9,10-oxide | Rattus norvegicus |
| 3.3.2.9 | 9 | - |
- |
Mus musculus |
| 3.3.2.9 | 9 | - |
hydration of styrene oxide in sodium phosphate buffer | Rattus norvegicus |
| 3.3.2.9 | 9.4 | - |
somewhat higher than, hydration of styrene oxide in glycine buffer | Rattus norvegicus |
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Release 2023.1 (January 2023)
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