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Literature summary extracted from
- Molecular properties and biological functions of microsomal epoxide hydrase (1980), Annu. Rev. Pharmacol. Toxicol., 20, 513-531.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.3.2.9 | Lipid | above the critrical micelle concentration gives kinetic pattern that mimics competitive inhibition | Rattus norvegicus |  |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.3.2.9 | additional information | - |
additional information | - |
Rattus norvegicus |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.3.2.9 | microsome | - |
Homo sapiens | - |
- |
| 3.3.2.9 | microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.3.2.9 | additional information | Homo sapiens | - |
? | - |
? | |
| 3.3.2.9 | additional information | Rattus norvegicus | role in benzopyrene-induced mutagenesis and carcinogenesis | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.3.2.9 | Homo sapiens | - |
- |
- |
| 3.3.2.9 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.3.2.9 | liver | - |
Homo sapiens | - |
| 3.3.2.9 | liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.3.2.9 | 7-methylbenzoanthracene + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 3.3.2.9 | benzopyrene 4,5-oxide + H2O | - |
Homo sapiens | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| 3.3.2.9 | benzopyrene 4,5-oxide + H2O | - |
Rattus norvegicus | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| 3.3.2.9 | dibenzoanthracene + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 3.3.2.9 | additional information | - |
Homo sapiens | ? | - |
? | |
| 3.3.2.9 | additional information | role in benzopyrene-induced mutagenesis and carcinogenesis | Rattus norvegicus | ? | - |
? | |
| 3.3.2.9 | octene 1,2-oxide + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.3.2.9 | octene 1,2-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 3.3.2.9 | styrene 7,8-oxide + H2O | - |
Homo sapiens | styrene glycol | - |
? | |
| 3.3.2.9 | styrene 7,8-oxide + H2O | - |
Rattus norvegicus | styrene glycol | - |
? | |
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