Reference Id = 208877 - BRENDA Enzyme Database

Activating Compound

EC Number	Activating Compound	Comment	Organism
3.3.2.9	additional information	induction of the enzyme by clofibrate and di(2-ethylhexyl)phthalate	Mus musculus
3.3.2.9	additional information	induction of the enzyme by clofibrate and di(2-ethylhexyl)phthalate	Homo sapiens
3.3.2.9	additional information	induction of the enzyme by clofibrate and di(2-ethylhexyl)phthalate	Rattus norvegicus
3.3.2.9	additional information	induction of the enzyme by clofibrate and di(2-ethylhexyl)phthalate	Oryctolagus cuniculus
3.3.2.9	additional information	induction of the enzyme by clofibrate and di(2-ethylhexyl)phthalate	Macaca mulatta
3.3.2.10	1-(2-cyanophenyl)-imidazole	-	Mus musculus
3.3.2.10	1-(2-cyanophenyl)-imidazole	-	Homo sapiens
3.3.2.10	1-(2-cyanophenyl)-imidazole	-	Rattus norvegicus
3.3.2.10	1-(2-cyanophenyl)-imidazole	-	Oryctolagus cuniculus
3.3.2.10	1-(2-cyanophenyl)-imidazole	-	Macaca mulatta
3.3.2.10	1-(2-Isopropylphenyl)-imidazole	-	Mus musculus
3.3.2.10	1-(2-Isopropylphenyl)-imidazole	-	Homo sapiens
3.3.2.10	1-(2-Isopropylphenyl)-imidazole	-	Rattus norvegicus
3.3.2.10	1-(2-Isopropylphenyl)-imidazole	-	Oryctolagus cuniculus
3.3.2.10	1-(2-Isopropylphenyl)-imidazole	-	Macaca mulatta
3.3.2.10	4-azafluorene	-	Mus musculus
3.3.2.10	4-azafluorene	-	Homo sapiens
3.3.2.10	4-azafluorene	-	Rattus norvegicus
3.3.2.10	4-azafluorene	-	Oryctolagus cuniculus
3.3.2.10	4-azafluorene	-	Macaca mulatta
3.3.2.10	4-phenylpyridine	-	Mus musculus
3.3.2.10	4-phenylpyridine	-	Homo sapiens
3.3.2.10	4-phenylpyridine	-	Rattus norvegicus
3.3.2.10	4-phenylpyridine	-	Oryctolagus cuniculus
3.3.2.10	4-phenylpyridine	-	Macaca mulatta
3.3.2.10	5,6-benzoflavone	-	Mus musculus
3.3.2.10	5,6-benzoflavone	-	Homo sapiens
3.3.2.10	5,6-benzoflavone	-	Rattus norvegicus
3.3.2.10	5,6-benzoflavone	-	Oryctolagus cuniculus
3.3.2.10	5,6-benzoflavone	-	Macaca mulatta
3.3.2.10	7,8-Benzoflavone	-	Mus musculus
3.3.2.10	7,8-Benzoflavone	-	Homo sapiens
3.3.2.10	7,8-Benzoflavone	-	Rattus norvegicus
3.3.2.10	7,8-Benzoflavone	-	Oryctolagus cuniculus
3.3.2.10	7,8-Benzoflavone	-	Macaca mulatta
3.3.2.10	9-fluorenone	-	Mus musculus
3.3.2.10	9-fluorenone	-	Homo sapiens
3.3.2.10	9-fluorenone	-	Rattus norvegicus
3.3.2.10	9-fluorenone	-	Oryctolagus cuniculus
3.3.2.10	9-fluorenone	-	Macaca mulatta
3.3.2.10	benzil	-	Mus musculus
3.3.2.10	benzil	-	Homo sapiens
3.3.2.10	benzil	-	Rattus norvegicus
3.3.2.10	benzil	-	Oryctolagus cuniculus
3.3.2.10	benzil	-	Macaca mulatta
3.3.2.10	benzophenone	-	Mus musculus
3.3.2.10	benzophenone	-	Homo sapiens
3.3.2.10	benzophenone	-	Rattus norvegicus
3.3.2.10	benzophenone	-	Oryctolagus cuniculus
3.3.2.10	benzophenone	-	Macaca mulatta
3.3.2.10	benzyl phenyl ketone	-	Mus musculus
3.3.2.10	benzyl phenyl ketone	-	Homo sapiens
3.3.2.10	benzyl phenyl ketone	-	Rattus norvegicus
3.3.2.10	benzyl phenyl ketone	-	Oryctolagus cuniculus
3.3.2.10	benzyl phenyl ketone	-	Macaca mulatta
3.3.2.10	chalcone	-	Mus musculus
3.3.2.10	chalcone	-	Homo sapiens
3.3.2.10	chalcone	-	Rattus norvegicus
3.3.2.10	chalcone	-	Oryctolagus cuniculus
3.3.2.10	chalcone	-	Macaca mulatta
3.3.2.10	Chalcone oxide	-	Mus musculus
3.3.2.10	Chalcone oxide	-	Homo sapiens
3.3.2.10	Chalcone oxide	-	Rattus norvegicus
3.3.2.10	Chalcone oxide	-	Oryctolagus cuniculus
3.3.2.10	Chalcone oxide	-	Macaca mulatta
3.3.2.10	cyclobenzaprine	-	Mus musculus
3.3.2.10	cyclobenzaprine	-	Homo sapiens
3.3.2.10	cyclobenzaprine	-	Rattus norvegicus
3.3.2.10	cyclobenzaprine	-	Oryctolagus cuniculus
3.3.2.10	cyclobenzaprine	-	Macaca mulatta
3.3.2.10	cyclobenzaprine 9,10-epoxide	-	Mus musculus
3.3.2.10	cyclobenzaprine 9,10-epoxide	-	Homo sapiens
3.3.2.10	cyclobenzaprine 9,10-epoxide	-	Rattus norvegicus
3.3.2.10	cyclobenzaprine 9,10-epoxide	-	Oryctolagus cuniculus
3.3.2.10	cyclobenzaprine 9,10-epoxide	-	Macaca mulatta
3.3.2.10	diphenylcyclopropenone	-	Mus musculus
3.3.2.10	diphenylcyclopropenone	-	Homo sapiens
3.3.2.10	diphenylcyclopropenone	-	Rattus norvegicus
3.3.2.10	diphenylcyclopropenone	-	Oryctolagus cuniculus
3.3.2.10	diphenylcyclopropenone	-	Macaca mulatta
3.3.2.10	ellipticine	-	Mus musculus
3.3.2.10	ellipticine	-	Homo sapiens
3.3.2.10	ellipticine	-	Rattus norvegicus
3.3.2.10	ellipticine	-	Oryctolagus cuniculus
3.3.2.10	ellipticine	-	Macaca mulatta
3.3.2.10	ethanol	-	Mus musculus
3.3.2.10	ethanol	-	Homo sapiens
3.3.2.10	ethanol	-	Rattus norvegicus
3.3.2.10	ethanol	-	Oryctolagus cuniculus
3.3.2.10	ethanol	-	Macaca mulatta
3.3.2.10	flavone	-	Mus musculus
3.3.2.10	flavone	-	Homo sapiens
3.3.2.10	flavone	-	Rattus norvegicus
3.3.2.10	flavone	-	Oryctolagus cuniculus
3.3.2.10	flavone	-	Macaca mulatta
3.3.2.10	harman	-	Mus musculus
3.3.2.10	harman	-	Homo sapiens
3.3.2.10	harman	-	Rattus norvegicus
3.3.2.10	harman	-	Oryctolagus cuniculus
3.3.2.10	harman	-	Macaca mulatta
3.3.2.10	Isoquinoline	-	Mus musculus
3.3.2.10	Isoquinoline	-	Homo sapiens
3.3.2.10	Isoquinoline	-	Rattus norvegicus
3.3.2.10	Isoquinoline	-	Oryctolagus cuniculus
3.3.2.10	Isoquinoline	-	Macaca mulatta
3.3.2.10	Metyrapone	-	Mus musculus
3.3.2.10	Metyrapone	-	Homo sapiens
3.3.2.10	Metyrapone	-	Rattus norvegicus
3.3.2.10	Metyrapone	-	Oryctolagus cuniculus
3.3.2.10	Metyrapone	-	Macaca mulatta
3.3.2.10	additional information	the enzyme is induced by several substances, e.g. 2-acetylfluorene, alpha-1-acetylmethadol, butylated hydroxyanisole, butylated hydroxytoluene, chalcone, gamma-chlordane, 1,2-dibromo-3-chloropropane, ethoxyquin, isosafrole, 3-methylcholanthrene, alpha-naphthoflavone, phenobarbital, polychlorinated and/or polybrominated biphenyls, pregnenolone-16alpha-carbonitrile, and trans-stilbene oxide	Mus musculus
3.3.2.10	additional information	the enzyme is induced by several substances, e.g. 2-acetylfluorene, alpha-1-acetylmethadol, butylated hydroxyanisole, butylated hydroxytoluene, chalcone, gamma-chlordane, 1,2-dibromo-3-chloropropane, ethoxyquin, isosafrole, 3-methylcholanthrene, alpha-naphthoflavone, phenobarbital, polychlorinated and/or polybrominated biphenyls, pregnenolone-16alpha-carbonitrile, and trans-stilbene oxide	Homo sapiens
3.3.2.10	additional information	the enzyme is induced by several substances, e.g. 2-acetylfluorene, alpha-1-acetylmethadol, butylated hydroxyanisole, butylated hydroxytoluene, chalcone, gamma-chlordane, 1,2-dibromo-3-chloropropane, ethoxyquin, isosafrole, 3-methylcholanthrene, alpha-naphthoflavone, phenobarbital, polychlorinated and/or polybrominated biphenyls, pregnenolone-16alpha-carbonitrile, and trans-stilbene oxide	Rattus norvegicus
3.3.2.10	additional information	the enzyme is induced by several substances, e.g. 2-acetylfluorene, alpha-1-acetylmethadol, butylated hydroxyanisole, butylated hydroxytoluene, chalcone, gamma-chlordane, 1,2-dibromo-3-chloropropane, ethoxyquin, isosafrole, 3-methylcholanthrene, alpha-naphthoflavone, phenobarbital, polychlorinated and/or polybrominated biphenyls, pregnenolone-16alpha-carbonitrile, and trans-stilbene oxide	Oryctolagus cuniculus
3.3.2.10	additional information	the enzyme is induced by several substances, e.g. 2-acetylfluorene, alpha-1-acetylmethadol, butylated hydroxyanisole, butylated hydroxytoluene, chalcone, gamma-chlordane, 1,2-dibromo-3-chloropropane, ethoxyquin, isosafrole, 3-methylcholanthrene, alpha-naphthoflavone, phenobarbital, polychlorinated and/or polybrominated biphenyls, pregnenolone-16alpha-carbonitrile, and trans-stilbene oxide	Macaca mulatta
3.3.2.10	norharman	-	Mus musculus
3.3.2.10	norharman	-	Homo sapiens
3.3.2.10	norharman	-	Rattus norvegicus
3.3.2.10	norharman	-	Oryctolagus cuniculus
3.3.2.10	norharman	-	Macaca mulatta
3.3.2.10	propyl phenyl ketone	-	Mus musculus
3.3.2.10	propyl phenyl ketone	-	Homo sapiens
3.3.2.10	propyl phenyl ketone	-	Rattus norvegicus
3.3.2.10	propyl phenyl ketone	-	Oryctolagus cuniculus
3.3.2.10	propyl phenyl ketone	-	Macaca mulatta
3.3.2.10	Quinoline	-	Mus musculus
3.3.2.10	Quinoline	-	Homo sapiens
3.3.2.10	Quinoline	-	Rattus norvegicus
3.3.2.10	Quinoline	-	Oryctolagus cuniculus
3.3.2.10	Quinoline	-	Macaca mulatta

Inhibitors

EC Number	Inhibitors	Comment	Organism
3.3.2.9	1,1,1-Trichloropropene 2,3-oxide	-	Homo sapiens
3.3.2.9	1,1,1-Trichloropropene 2,3-oxide	-	Macaca mulatta
3.3.2.9	1,1,1-Trichloropropene 2,3-oxide	-	Mus musculus
3.3.2.9	1,1,1-Trichloropropene 2,3-oxide	-	Oryctolagus cuniculus
3.3.2.9	1,1,1-Trichloropropene 2,3-oxide	-	Rattus norvegicus
3.3.2.9	2-Bromo-4'-nitroacetophenone	-	Homo sapiens
3.3.2.9	2-Bromo-4'-nitroacetophenone	-	Macaca mulatta
3.3.2.9	2-Bromo-4'-nitroacetophenone	-	Mus musculus
3.3.2.9	2-Bromo-4'-nitroacetophenone	-	Oryctolagus cuniculus
3.3.2.9	2-Bromo-4'-nitroacetophenone	-	Rattus norvegicus
3.3.2.9	Cu2+	-	Homo sapiens
3.3.2.9	Cu2+	-	Macaca mulatta
3.3.2.9	Cu2+	-	Mus musculus
3.3.2.9	Cu2+	-	Oryctolagus cuniculus
3.3.2.9	Cu2+	-	Rattus norvegicus
3.3.2.10	1,1,1-Trichloropropene 2,3-oxide	-	Homo sapiens
3.3.2.10	1,1,1-Trichloropropene 2,3-oxide	-	Macaca mulatta
3.3.2.10	1,1,1-Trichloropropene 2,3-oxide	-	Mus musculus
3.3.2.10	1,1,1-Trichloropropene 2,3-oxide	-	Oryctolagus cuniculus
3.3.2.10	1,1,1-Trichloropropene 2,3-oxide	-	Rattus norvegicus
3.3.2.10	2-Bromo-4'-nitroacetophenone	-	Homo sapiens
3.3.2.10	2-Bromo-4'-nitroacetophenone	-	Macaca mulatta
3.3.2.10	2-Bromo-4'-nitroacetophenone	-	Mus musculus
3.3.2.10	2-Bromo-4'-nitroacetophenone	-	Oryctolagus cuniculus
3.3.2.10	2-Bromo-4'-nitroacetophenone	-	Rattus norvegicus
3.3.2.10	cyclohexane 1,2-oxide	-	Homo sapiens
3.3.2.10	cyclohexane 1,2-oxide	-	Macaca mulatta
3.3.2.10	cyclohexane 1,2-oxide	-	Mus musculus
3.3.2.10	cyclohexane 1,2-oxide	-	Oryctolagus cuniculus
3.3.2.10	cyclohexane 1,2-oxide	-	Rattus norvegicus
3.3.2.10	p-Hydroxymercuriphenylsulfonate	-	Homo sapiens
3.3.2.10	p-Hydroxymercuriphenylsulfonate	-	Macaca mulatta
3.3.2.10	p-Hydroxymercuriphenylsulfonate	-	Mus musculus
3.3.2.10	p-Hydroxymercuriphenylsulfonate	-	Oryctolagus cuniculus
3.3.2.10	p-Hydroxymercuriphenylsulfonate	-	Rattus norvegicus
3.3.2.10	styrene oxide	-	Homo sapiens
3.3.2.10	styrene oxide	-	Macaca mulatta
3.3.2.10	styrene oxide	-	Mus musculus
3.3.2.10	styrene oxide	-	Oryctolagus cuniculus
3.3.2.10	styrene oxide	-	Rattus norvegicus
3.3.2.10	substituted chalcone oxides	-	Homo sapiens
3.3.2.10	substituted chalcone oxides	-	Macaca mulatta
3.3.2.10	substituted chalcone oxides	-	Mus musculus
3.3.2.10	substituted chalcone oxides	-	Oryctolagus cuniculus
3.3.2.10	substituted chalcone oxides	-	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
3.3.2.9	soluble	-	Mus musculus	-	-
3.3.2.9	soluble	-	Homo sapiens	-	-
3.3.2.9	soluble	-	Rattus norvegicus	-	-
3.3.2.9	soluble	-	Oryctolagus cuniculus	-	-
3.3.2.9	soluble	-	Macaca mulatta	-	-
3.3.2.10	endoplasmic reticulum	rough and smooth	Mus musculus	5783	-
3.3.2.10	endoplasmic reticulum	rough and smooth	Homo sapiens	5783	-
3.3.2.10	endoplasmic reticulum	rough and smooth	Rattus norvegicus	5783	-
3.3.2.10	endoplasmic reticulum	rough and smooth	Oryctolagus cuniculus	5783	-
3.3.2.10	endoplasmic reticulum	rough and smooth	Macaca mulatta	5783	-
3.3.2.10	Golgi apparatus	-	Mus musculus	5794	-
3.3.2.10	Golgi apparatus	-	Homo sapiens	5794	-
3.3.2.10	Golgi apparatus	-	Rattus norvegicus	5794	-
3.3.2.10	Golgi apparatus	-	Oryctolagus cuniculus	5794	-
3.3.2.10	Golgi apparatus	-	Macaca mulatta	5794	-
3.3.2.10	membrane	-	Mus musculus	16020	-
3.3.2.10	membrane	-	Homo sapiens	16020	-
3.3.2.10	membrane	-	Rattus norvegicus	16020	-
3.3.2.10	membrane	-	Oryctolagus cuniculus	16020	-
3.3.2.10	membrane	-	Macaca mulatta	16020	-
3.3.2.10	additional information	highest level found in smooth endoplasmic reticulum, lower levels observed in rough endoplasmic reticulum, Golgi apparatus, nuclear membrane and plasma membrane. The enzyme is synthesized in membrane-bound polysomes and inserted cotranslationally into the endoplasmic reticulum	Mus musculus	-	-
3.3.2.10	additional information	highest level found in smooth endoplasmic reticulum, lower levels observed in rough endoplasmic reticulum, Golgi apparatus, nuclear membrane and plasma membrane. The enzyme is synthesized in membrane-bound polysomes and inserted cotranslationally into the endoplasmic reticulum	Homo sapiens	-	-
3.3.2.10	additional information	highest level found in smooth endoplasmic reticulum, lower levels observed in rough endoplasmic reticulum, Golgi apparatus, nuclear membrane and plasma membrane. The enzyme is synthesized in membrane-bound polysomes and inserted cotranslationally into the endoplasmic reticulum	Rattus norvegicus	-	-
3.3.2.10	additional information	highest level found in smooth endoplasmic reticulum, lower levels observed in rough endoplasmic reticulum, Golgi apparatus, nuclear membrane and plasma membrane. The enzyme is synthesized in membrane-bound polysomes and inserted cotranslationally into the endoplasmic reticulum	Oryctolagus cuniculus	-	-
3.3.2.10	additional information	highest level found in smooth endoplasmic reticulum, lower levels observed in rough endoplasmic reticulum, Golgi apparatus, nuclear membrane and plasma membrane. The enzyme is synthesized in membrane-bound polysomes and inserted cotranslationally into the endoplasmic reticulum	Macaca mulatta	-	-
3.3.2.10	nuclear membrane	-	Mus musculus	31965	-
3.3.2.10	nuclear membrane	-	Homo sapiens	31965	-
3.3.2.10	nuclear membrane	-	Rattus norvegicus	31965	-
3.3.2.10	nuclear membrane	-	Oryctolagus cuniculus	31965	-
3.3.2.10	nuclear membrane	-	Macaca mulatta	31965	-
3.3.2.10	plasma membrane	-	Mus musculus	5886	-
3.3.2.10	plasma membrane	-	Homo sapiens	5886	-
3.3.2.10	plasma membrane	-	Rattus norvegicus	5886	-
3.3.2.10	plasma membrane	-	Oryctolagus cuniculus	5886	-
3.3.2.10	plasma membrane	-	Macaca mulatta	5886	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.3.2.9	Homo sapiens	-	-	-
3.3.2.9	Macaca mulatta	-	-	-
3.3.2.9	Mus musculus	-	-	-
3.3.2.9	Oryctolagus cuniculus	-	-	-
3.3.2.9	Rattus norvegicus	-	-	-
3.3.2.10	Homo sapiens	-	-	-
3.3.2.10	Macaca mulatta	-	-	-
3.3.2.10	Mus musculus	-	-	-
3.3.2.10	Oryctolagus cuniculus	-	-	-
3.3.2.10	Rattus norvegicus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
3.3.2.9	partially 2.4fold from liver using PEG precipitation, and to homogeneity by ion exchange, hydrophobic interaction chromatography, and hydroxylapatite chromatography	Mus musculus
3.3.2.9	partially from liver	Homo sapiens
3.3.2.9	partially from liver	Oryctolagus cuniculus
3.3.2.10	from liver	Rattus norvegicus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.3.2.9	kidney	high activity	Mus musculus	-
3.3.2.9	kidney	high activity	Homo sapiens	-
3.3.2.9	kidney	high activity	Rattus norvegicus	-
3.3.2.9	kidney	high activity	Oryctolagus cuniculus	-
3.3.2.9	kidney	high activity	Macaca mulatta	-
3.3.2.9	liver	high activity	Mus musculus	-
3.3.2.9	liver	high activity	Homo sapiens	-
3.3.2.9	liver	high activity	Rattus norvegicus	-
3.3.2.9	liver	high activity	Oryctolagus cuniculus	-
3.3.2.9	liver	high activity	Macaca mulatta	-
3.3.2.9	testis	low activity	Mus musculus	-
3.3.2.9	testis	low activity	Homo sapiens	-
3.3.2.9	testis	low activity	Rattus norvegicus	-
3.3.2.9	testis	low activity	Oryctolagus cuniculus	-
3.3.2.9	testis	low activity	Macaca mulatta	-
3.3.2.10	kidney	high activity	Mus musculus	-
3.3.2.10	kidney	high activity	Homo sapiens	-
3.3.2.10	kidney	high activity	Rattus norvegicus	-
3.3.2.10	kidney	high activity	Oryctolagus cuniculus	-
3.3.2.10	kidney	high activity	Macaca mulatta	-
3.3.2.10	liver	high activity	Mus musculus	-
3.3.2.10	liver	high activity	Homo sapiens	-
3.3.2.10	liver	high activity	Rattus norvegicus	-
3.3.2.10	liver	high activity	Oryctolagus cuniculus	-
3.3.2.10	liver	high activity	Macaca mulatta	-
3.3.2.10	testis	high activity	Mus musculus	-
3.3.2.10	testis	high activity	Homo sapiens	-
3.3.2.10	testis	high activity	Rattus norvegicus	-
3.3.2.10	testis	high activity	Oryctolagus cuniculus	-
3.3.2.10	testis	high activity	Macaca mulatta	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
3.3.2.9	additional information	-	several analytical and activity assay methods	Mus musculus
3.3.2.9	additional information	-	several analytical and activity assay methods	Homo sapiens
3.3.2.9	additional information	-	several analytical and activity assay methods	Rattus norvegicus
3.3.2.9	additional information	-	several analytical and activity assay methods	Oryctolagus cuniculus
3.3.2.9	additional information	-	several analytical and activity assay methods	Macaca mulatta
3.3.2.10	additional information	-	several analytical and activity assay methods	Mus musculus
3.3.2.10	additional information	-	several analytical and activity assay methods	Homo sapiens
3.3.2.10	additional information	-	several analytical and activity assay methods	Rattus norvegicus
3.3.2.10	additional information	-	several analytical and activity assay methods	Oryctolagus cuniculus
3.3.2.10	additional information	-	several analytical and activity assay methods	Macaca mulatta

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.
3.3.2.9	cis-stilbene oxide + H2O	-	Mus musculus	(+)-(1R,2R)-1,2-diphenylethane-1,2-diol	-	?
3.3.2.9	cis-stilbene oxide + H2O	-	Homo sapiens	(+)-(1R,2R)-1,2-diphenylethane-1,2-diol	-	?
3.3.2.9	cis-stilbene oxide + H2O	-	Rattus norvegicus	(+)-(1R,2R)-1,2-diphenylethane-1,2-diol	-	?
3.3.2.9	cis-stilbene oxide + H2O	-	Oryctolagus cuniculus	(+)-(1R,2R)-1,2-diphenylethane-1,2-diol	-	?
3.3.2.9	cis-stilbene oxide + H2O	-	Macaca mulatta	(+)-(1R,2R)-1,2-diphenylethane-1,2-diol	-	?
3.3.2.9	clofibrate + H2O	-	Mus musculus	?	-	?
3.3.2.9	clofibrate + H2O	-	Homo sapiens	?	-	?
3.3.2.9	clofibrate + H2O	-	Rattus norvegicus	?	-	?
3.3.2.9	clofibrate + H2O	-	Oryctolagus cuniculus	?	-	?
3.3.2.9	clofibrate + H2O	-	Macaca mulatta	?	-	?
3.3.2.9	di(2-ethylhexyl)phthalate + H2O	-	Mus musculus	?	-	?
3.3.2.9	di(2-ethylhexyl)phthalate + H2O	-	Homo sapiens	?	-	?
3.3.2.9	di(2-ethylhexyl)phthalate + H2O	-	Rattus norvegicus	?	-	?
3.3.2.9	di(2-ethylhexyl)phthalate + H2O	-	Oryctolagus cuniculus	?	-	?
3.3.2.9	di(2-ethylhexyl)phthalate + H2O	-	Macaca mulatta	?	-	?
3.3.2.9	additional information	substrate specificity, no activity with 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene,i.e. HEOM, 2-acetylaminofluorene, arochlor 1254, and benzopyrene 4,5-oxide, the cytosolic enzyme hydrates epoxides on cyclic systems very slowly, but hydrates a wide variety of aliphatic epoxides rapidly, trisubstituted terpenoid epoxides show low Km-valus, fatty acid and ester epoxides are hydrated very quickly	Macaca mulatta	?	-	?
3.3.2.9	additional information	substrate specificity, no activity with 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene,i.e. HEOM, 2-acetylaminofluorene, arochlor 1254, and benzopyrene 4,5-oxide, the cytosolic enzyme hydrates epoxides on cyclic sytems very slowly, but hydrates a wide variety of aliphatic epoxides rapidly, trisubstituted terpenoid epoxides show low Km-values, fatty acid and ester epoxides are hydrated very quickly	Mus musculus	?	-	?
3.3.2.9	additional information	substrate specificity, no activity with 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene,i.e. HEOM, 2-acetylaminofluorene, arochlor 1254, and benzopyrene 4,5-oxide, the cytosolic enzyme hydrates epoxides on cyclic sytems very slowly, but hydrates a wide variety of aliphatic epoxides rapidly, trisubstituted terpenoid epoxides show low Km-values, fatty acid and ester epoxides are hydrated very quickly	Homo sapiens	?	-	?
3.3.2.9	additional information	substrate specificity, no activity with 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene,i.e. HEOM, 2-acetylaminofluorene, arochlor 1254, and benzopyrene 4,5-oxide, the cytosolic enzyme hydrates epoxides on cyclic sytems very slowly, but hydrates a wide variety of aliphatic epoxides rapidly, trisubstituted terpenoid epoxides show low Km-values, fatty acid and ester epoxides are hydrated very quickly	Rattus norvegicus	?	-	?
3.3.2.9	additional information	substrate specificity, no activity with 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene,i.e. HEOM, 2-acetylaminofluorene, arochlor 1254, and benzopyrene 4,5-oxide, the cytosolic enzyme hydrates epoxides on cyclic sytems very slowly, but hydrates a wide variety of aliphatic epoxides rapidly, trisubstituted terpenoid epoxides show low Km-values, fatty acid and ester epoxides are hydrated very quickly	Oryctolagus cuniculus	?	-	?
3.3.2.9	styrene oxide + H2O	-	Mus musculus	1-phenylethane-1,2-diol	-	?
3.3.2.9	styrene oxide + H2O	-	Homo sapiens	1-phenyl-ethane-1,2-diol	-	?
3.3.2.9	styrene oxide + H2O	-	Rattus norvegicus	1-phenyl-ethane-1,2-diol	-	?
3.3.2.9	styrene oxide + H2O	-	Oryctolagus cuniculus	1-phenyl-ethane-1,2-diol	-	?
3.3.2.9	styrene oxide + H2O	-	Macaca mulatta	1-phenyl-ethane-1,2-diol	-	?
3.3.2.9	trans-9,10-epoxystearate + H2O	-	Mus musculus	9,10-dihydroxy-octadecanoic acid	-	?
3.3.2.9	trans-9,10-epoxystearate + H2O	-	Homo sapiens	9,10-dihydroxy-octadecanoic acid	-	?
3.3.2.9	trans-9,10-epoxystearate + H2O	-	Rattus norvegicus	9,10-dihydroxy-octadecanoic acid	-	?
3.3.2.9	trans-9,10-epoxystearate + H2O	-	Oryctolagus cuniculus	9,10-dihydroxy-octadecanoic acid	-	?
3.3.2.9	trans-9,10-epoxystearate + H2O	-	Macaca mulatta	9,10-dihydroxy-octadecanoic acid	-	?
3.3.2.10	1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O	i.e. HEOM	Mus musculus	?	-	?
3.3.2.10	1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O	i.e. HEOM	Homo sapiens	?	-	?
3.3.2.10	1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O	i.e. HEOM	Rattus norvegicus	?	-	?
3.3.2.10	1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O	i.e. HEOM	Oryctolagus cuniculus	?	-	?
3.3.2.10	1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O	i.e. HEOM	Macaca mulatta	?	-	?
3.3.2.10	2,3-squalene oxide + H2O	-	Mus musculus	?	-	?
3.3.2.10	2,3-squalene oxide + H2O	-	Homo sapiens	?	-	?
3.3.2.10	2,3-squalene oxide + H2O	-	Rattus norvegicus	?	-	?
3.3.2.10	2,3-squalene oxide + H2O	-	Oryctolagus cuniculus	?	-	?
3.3.2.10	2,3-squalene oxide + H2O	-	Macaca mulatta	?	-	?
3.3.2.10	2-acetylaminofluorene + H2O	-	Mus musculus	?	-	?
3.3.2.10	2-acetylaminofluorene + H2O	-	Homo sapiens	?	-	?
3.3.2.10	2-acetylaminofluorene + H2O	-	Rattus norvegicus	?	-	?
3.3.2.10	2-acetylaminofluorene + H2O	-	Oryctolagus cuniculus	?	-	?
3.3.2.10	2-acetylaminofluorene + H2O	-	Macaca mulatta	?	-	?
3.3.2.10	4-nitrostyrene oxide + H2O	-	Mus musculus	?	-	?
3.3.2.10	4-nitrostyrene oxide + H2O	-	Homo sapiens	?	-	?
3.3.2.10	4-nitrostyrene oxide + H2O	-	Rattus norvegicus	?	-	?
3.3.2.10	4-nitrostyrene oxide + H2O	-	Oryctolagus cuniculus	?	-	?
3.3.2.10	4-nitrostyrene oxide + H2O	-	Macaca mulatta	?	-	?
3.3.2.10	arochlor 1254 + H2O	-	Mus musculus	?	-	?
3.3.2.10	arochlor 1254 + H2O	-	Homo sapiens	?	-	?
3.3.2.10	arochlor 1254 + H2O	-	Rattus norvegicus	?	-	?
3.3.2.10	arochlor 1254 + H2O	-	Oryctolagus cuniculus	?	-	?
3.3.2.10	arochlor 1254 + H2O	-	Macaca mulatta	?	-	?
3.3.2.10	benzopyrene 4,5-oxide + H2O	-	Mus musculus	(-)benzopyrene 4,5-dihydrodiol	-	?
3.3.2.10	benzopyrene 4,5-oxide + H2O	-	Homo sapiens	(-)benzopyrene 4,5-dihydrodiol	-	?
3.3.2.10	benzopyrene 4,5-oxide + H2O	-	Rattus norvegicus	(-)benzopyrene 4,5-dihydrodiol	-	?
3.3.2.10	benzopyrene 4,5-oxide + H2O	-	Oryctolagus cuniculus	(-)benzopyrene 4,5-dihydrodiol	-	?
3.3.2.10	benzopyrene 4,5-oxide + H2O	-	Macaca mulatta	(-)benzopyrene 4,5-dihydrodiol	-	?
3.3.2.10	cis-stilbene oxide + H2O	-	Mus musculus	?	-	?
3.3.2.10	cis-stilbene oxide + H2O	-	Homo sapiens	?	-	?
3.3.2.10	cis-stilbene oxide + H2O	-	Rattus norvegicus	?	-	?
3.3.2.10	cis-stilbene oxide + H2O	-	Oryctolagus cuniculus	?	-	?
3.3.2.10	cis-stilbene oxide + H2O	-	Macaca mulatta	?	-	?
3.3.2.10	clofibrate + H2O	-	Mus musculus	?	-	?
3.3.2.10	clofibrate + H2O	-	Homo sapiens	?	-	?
3.3.2.10	clofibrate + H2O	-	Rattus norvegicus	?	-	?
3.3.2.10	clofibrate + H2O	-	Oryctolagus cuniculus	?	-	?
3.3.2.10	clofibrate + H2O	-	Macaca mulatta	?	-	?
3.3.2.10	di(2-ethylhexyl)phthalate + H2O	-	Mus musculus	?	-	?
3.3.2.10	di(2-ethylhexyl)phthalate + H2O	-	Homo sapiens	?	-	?
3.3.2.10	di(2-ethylhexyl)phthalate + H2O	-	Rattus norvegicus	?	-	?
3.3.2.10	di(2-ethylhexyl)phthalate + H2O	-	Oryctolagus cuniculus	?	-	?
3.3.2.10	di(2-ethylhexyl)phthalate + H2O	-	Macaca mulatta	?	-	?
3.3.2.10	additional information	substrate specificity, the microsomal enzyme rapidly hydrolyzes epoxides on cyclic systems as well as mono, 1,1-di and cis-1,2-disubstituted epoxides	Mus musculus	?	-	?
3.3.2.10	additional information	substrate specificity, the microsomal enzyme rapidly hydrolyzes epoxides on cyclic systems as well as mono, 1,1-di and cis-1,2-disubstituted epoxides	Homo sapiens	?	-	?
3.3.2.10	additional information	substrate specificity, the microsomal enzyme rapidly hydrolyzes epoxides on cyclic systems as well as mono, 1,1-di and cis-1,2-disubstituted epoxides	Rattus norvegicus	?	-	?
3.3.2.10	additional information	substrate specificity, the microsomal enzyme rapidly hydrolyzes epoxides on cyclic systems as well as mono, 1,1-di and cis-1,2-disubstituted epoxides	Oryctolagus cuniculus	?	-	?
3.3.2.10	additional information	substrate specificity, the microsomal enzyme rapidly hydrolyzes epoxides on cyclic systems as well as mono, 1,1-di and cis-1,2-disubstituted epoxides	Macaca mulatta	?	-	?
3.3.2.10	phenanthrene-9,10-oxide + H2O	-	Mus musculus	?	-	?
3.3.2.10	phenanthrene-9,10-oxide + H2O	-	Homo sapiens	?	-	?
3.3.2.10	phenanthrene-9,10-oxide + H2O	-	Rattus norvegicus	?	-	?
3.3.2.10	phenanthrene-9,10-oxide + H2O	-	Oryctolagus cuniculus	?	-	?
3.3.2.10	phenanthrene-9,10-oxide + H2O	-	Macaca mulatta	?	-	?
3.3.2.10	phenobarbital + H2O	-	Mus musculus	?	-	?
3.3.2.10	phenobarbital + H2O	-	Homo sapiens	?	-	?
3.3.2.10	phenobarbital + H2O	-	Rattus norvegicus	?	-	?
3.3.2.10	phenobarbital + H2O	-	Oryctolagus cuniculus	?	-	?
3.3.2.10	phenobarbital + H2O	-	Macaca mulatta	?	-	?
3.3.2.10	styrene oxide + H2O	-	Mus musculus	?	-	?
3.3.2.10	styrene oxide + H2O	-	Homo sapiens	?	-	?
3.3.2.10	styrene oxide + H2O	-	Rattus norvegicus	?	-	?
3.3.2.10	styrene oxide + H2O	-	Oryctolagus cuniculus	?	-	?
3.3.2.10	styrene oxide + H2O	-	Macaca mulatta	?	-	?
3.3.2.10	trans-9,10-epoxystearate + H2O	-	Mus musculus	?	-	?
3.3.2.10	trans-9,10-epoxystearate + H2O	-	Homo sapiens	?	-	?
3.3.2.10	trans-9,10-epoxystearate + H2O	-	Rattus norvegicus	?	-	?
3.3.2.10	trans-9,10-epoxystearate + H2O	-	Oryctolagus cuniculus	?	-	?
3.3.2.10	trans-9,10-epoxystearate + H2O	-	Macaca mulatta	?	-	?
3.3.2.10	trans-ethyl styrene oxide + H2O	-	Mus musculus	?	-	?
3.3.2.10	trans-ethyl styrene oxide + H2O	-	Homo sapiens	?	-	?
3.3.2.10	trans-ethyl styrene oxide + H2O	-	Rattus norvegicus	?	-	?
3.3.2.10	trans-ethyl styrene oxide + H2O	-	Oryctolagus cuniculus	?	-	?
3.3.2.10	trans-ethyl styrene oxide + H2O	-	Macaca mulatta	?	-	?
3.3.2.10	trans-stilbene oxide + H2O	-	Mus musculus	?	-	?
3.3.2.10	trans-stilbene oxide + H2O	-	Homo sapiens	?	-	?
3.3.2.10	trans-stilbene oxide + H2O	-	Rattus norvegicus	?	-	?
3.3.2.10	trans-stilbene oxide + H2O	-	Oryctolagus cuniculus	?	-	?
3.3.2.10	trans-stilbene oxide + H2O	-	Macaca mulatta	?	-	?

Literature summary extracted from

Activating Compound

Inhibitors

Localization

Organism

Purification (Commentary)

Source Tissue

Specific Activity [micromol/min/mg]

Substrates and Products (Substrate)