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Literature summary extracted from

  • Carlsen, R.B.; Pierce, J.G.
    Purification and properties of an alpha-L-fucosidase from rat epididymis (1972), J. Biol. Chem., 247, 23-32.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.51 Ag+ effective inhibition at 5 mM Rattus sp.
3.2.1.51 Cd2+ effective inhibition at 5 mM Rattus sp.
3.2.1.51 Cu2+ effective inhibition at 5 mM Rattus sp.
3.2.1.51 Hg2+ effective inhibition at 5 mM Rattus sp.
3.2.1.51 Ni2+ effective inhibition at 5 mM Rattus sp.
3.2.1.51 Pb2+ effective inhibition at 5 mM Rattus sp.
3.2.1.51 Zn-acetate more than 90% inhibition at 5 mM Rattus sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.1.51 47000
-
 2 * 60000 + 2 * 2 * 47000, SDS-PAGE Rattus sp.
3.2.1.51 60000
-
 2 * 60000 + 2 * 2 * 47000, SDS-PAGE Rattus sp.
3.2.1.51 210000 220000 sedimentation equilibrium centrifugation Rattus sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.51 IgG Fc peptide + H2O Rattus sp. human, rabbit, horse alpha-L-fucose + ?
-
 ?
3.2.1.51 IgG L peptide + H2O Rattus sp.
-
 alpha-L-fucose + ?
-
 ?
3.2.1.51 LH-beta peptic glycopeptide + H2O Rattus sp.
-
 alpha-L-fucose + ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.51 Rattus sp.
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.2.1.51 glycoprotein 0.6% carbohydrate per native molecule Rattus sp.

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.51 near homogeneity Rattus sp.

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.51 epididymis
-
 Rattus sp.
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.2.1.51 12.8
-
-
 Rattus sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.51 4-nitrophenyl-alpha-L-fucopyranoside + H2O
-
 Rattus sp. 4-nitrophenol + alpha-L-fucose
-
 ?
3.2.1.51 IgG Fc peptide + H2O from human, rabbit, horse Rattus sp. alpha-L-fucose + ?
-
 ?
3.2.1.51 IgG Fc peptide + H2O human, rabbit, horse Rattus sp. alpha-L-fucose + ?
-
 ?
3.2.1.51 IgG L peptide + H2O
-
 Rattus sp. alpha-L-fucose + ?
-
 ?
3.2.1.51 LH-beta peptic glycopeptide + H2O
-
 Rattus sp. alpha-L-fucose + ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.2.1.51 tetramer 2 * 60000 + 2 * 2 * 47000, SDS-PAGE Rattus sp.

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.51 6.3
-
-
 Rattus sp.