BRENDA - Enzyme Database

Purification and characterization of alpha-L-fucosidase from the liver of a fucosidosis patient

Ahadeff, J.A; Andrews-Smith, G.L.; Biochem. J. 187, 45-51 (1980)

Data extracted from this reference:

KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.2.1.51
0.14
-
4-methylumbelliferyl-alpha-L-fucopyranoside
4-5fold increase in fucosidosis patients
Homo sapiens
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.2.1.51
Homo sapiens
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.2.1.51
liver
characterization of alpha-fucosidase from fucosidosis patients
Homo sapiens
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.2.1.51
4-methylumbelliferyl-alpha-L-fucopyranoside + H2O
-
208723
Homo sapiens
4-methylumbelliferone + alpha-L-fucose
-
208723
Homo sapiens
?
Temperature Stability [°C]
EC Number
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
3.2.1.51
50
55
greatly decreased thermostability in fucosidosis patients
Homo sapiens
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.2.1.51
0.14
-
4-methylumbelliferyl-alpha-L-fucopyranoside
4-5fold increase in fucosidosis patients
Homo sapiens
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.2.1.51
liver
characterization of alpha-fucosidase from fucosidosis patients
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.2.1.51
4-methylumbelliferyl-alpha-L-fucopyranoside + H2O
-
208723
Homo sapiens
4-methylumbelliferone + alpha-L-fucose
-
208723
Homo sapiens
?
Temperature Stability [°C] (protein specific)
EC Number
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
3.2.1.51
50
55
greatly decreased thermostability in fucosidosis patients
Homo sapiens