BRENDA - Enzyme Database

Characterization of mouse liver alpha-L-fucosidase. Demonstration of unusual basic isoelectric forms of the enzyme that appear to be developmentally regulated

Laury-Kleintop, L.D.; Damjanov, I.; Alhadeff, J.A.; Biochem. J. 230, 75-82 (1985)

Data extracted from this reference:

KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.2.1.51
0.05
0.06
4-methylumbelliferyl-alpha-L-fucopyranoside
-
Mus musculus
3.2.1.51
0.05
0.06
4-methylumbelliferyl-alpha-L-fucopyranoside
-
Homo sapiens
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.2.1.51
Homo sapiens
-
-
-
3.2.1.51
Mus musculus
-
-
-
Posttranslational Modification
EC Number
Posttranslational Modification
Commentary
Organism
3.2.1.51
glycoprotein
sialylated
Mus musculus
3.2.1.51
glycoprotein
-
Homo sapiens
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.2.1.51
fetus
-
Mus musculus
-
3.2.1.51
liver
-
Mus musculus
-
3.2.1.51
liver
-
Homo sapiens
-
3.2.1.51
placenta
-
Mus musculus
-
3.2.1.51
placenta
-
Homo sapiens
-
Storage Stability
EC Number
Storage Stability
Organism
3.2.1.51
2-4°C, 29 days
Mus musculus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.2.1.51
4-methylumbelliferyl-alpha-L-fucopyranoside + H2O
-
208715
Mus musculus
4-methylumbelliferone + alpha-L-fucose
-
208715
Mus musculus
?
3.2.1.51
4-methylumbelliferyl-alpha-L-fucopyranoside + H2O
-
208715
Homo sapiens
4-methylumbelliferone + alpha-L-fucose
-
208715
Homo sapiens
?
Temperature Stability [°C]
EC Number
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
3.2.1.51
50
-
-
Homo sapiens
3.2.1.51
50
-
from mouse liver: more labile against inactivation than from human liver or mouse placental enzymes
Mus musculus
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.2.1.51
4.3
-
one of two pH-optima
Homo sapiens
3.2.1.51
5.5
-
-
Homo sapiens
3.2.1.51
5.5
-
-
Mus musculus
3.2.1.51
6
6.5
-
Homo sapiens
3.2.1.51
6.8
-
one of two pH-optima
Homo sapiens
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.2.1.51
0.05
0.06
4-methylumbelliferyl-alpha-L-fucopyranoside
-
Mus musculus
3.2.1.51
0.05
0.06
4-methylumbelliferyl-alpha-L-fucopyranoside
-
Homo sapiens
Posttranslational Modification (protein specific)
EC Number
Posttranslational Modification
Commentary
Organism
3.2.1.51
glycoprotein
sialylated
Mus musculus
3.2.1.51
glycoprotein
-
Homo sapiens
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.2.1.51
fetus
-
Mus musculus
-
3.2.1.51
liver
-
Mus musculus
-
3.2.1.51
liver
-
Homo sapiens
-
3.2.1.51
placenta
-
Mus musculus
-
3.2.1.51
placenta
-
Homo sapiens
-
Storage Stability (protein specific)
EC Number
Storage Stability
Organism
3.2.1.51
2-4°C, 29 days
Mus musculus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.2.1.51
4-methylumbelliferyl-alpha-L-fucopyranoside + H2O
-
208715
Mus musculus
4-methylumbelliferone + alpha-L-fucose
-
208715
Mus musculus
?
3.2.1.51
4-methylumbelliferyl-alpha-L-fucopyranoside + H2O
-
208715
Homo sapiens
4-methylumbelliferone + alpha-L-fucose
-
208715
Homo sapiens
?
Temperature Stability [°C] (protein specific)
EC Number
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
3.2.1.51
50
-
-
Homo sapiens
3.2.1.51
50
-
from mouse liver: more labile against inactivation than from human liver or mouse placental enzymes
Mus musculus
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.2.1.51
4.3
-
one of two pH-optima
Homo sapiens
3.2.1.51
5.5
-
-
Homo sapiens
3.2.1.51
5.5
-
-
Mus musculus
3.2.1.51
6
6.5
-
Homo sapiens
3.2.1.51
6.8
-
one of two pH-optima
Homo sapiens