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Literature summary extracted from

  • Abe, H.; Tanuma, S.
    Properties of poly(ADP-ribose) glycohydrolase purified from pig testis nuclei (1996), Arch. Biochem. Biophys., 336, 139-146.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.143 KCl 200 mM or more Sus scrofa
3.2.1.143 NaCl 200 mM or more Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.143 0.0054
-
 (ADP-D-ribose)15
-
 Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.1.143 nucleus
-
 Sus scrofa 5634
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.2.1.143 KCl 50-100 mM, stimulates Sus scrofa
3.2.1.143 NaCl 50-100 mM, stimulates Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.1.143 51000
-
 gel filtration Sus scrofa
3.2.1.143 58000
-
 1 * 58000, SDS-PAGE Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.143 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.143
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.143 testis
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.2.1.143 32.1
-
-
 Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.143 (ADP-D-ribose)15 + H2O
-
 Sus scrofa (ADP-ribose)14 + ADP-D-ribose
-
 ?
3.2.1.143 poly(ADP-ribose)n + H2O
-
 Sus scrofa ADP-ribose
-
 ?

Subunits

EC Number Subunits Comment Organism
3.2.1.143 monomer 1 * 58000, SDS-PAGE Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.143 7.2
-
-
 Sus scrofa

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.2.1.143 6 8.5 pH 6.0: about 50% of maximal activity, pH 8.5: about 35% of maximal activity Sus scrofa