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Literature summary extracted from
- 5'-Nucleotide phosphodiesterase and alkaline phosphatase in tumor cells: evidence for existence of novel species in the cytosol (1988), Biochim. Biophys. Acta, 966, 99-106.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.4.1 | dithiothreitol | tumor cell line, N-ethylmaleimide-sensitive | Mus musculus |  |
| 3.1.4.1 | dithiothreitol | tumor cell line, N-ethylmaleimide-sensitive | Homo sapiens | |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.4.1 | dithiothreitol | - |
Bos taurus | |
| 3.1.4.1 | dithiothreitol | - |
Homo sapiens | |
| 3.1.4.1 | dithiothreitol | - |
Mus musculus | |
| 3.1.4.1 | N-ethylmaleimide | tumor cell line, N-ethylmaleimide-sensitive | Homo sapiens | |
| 3.1.4.1 | N-ethylmaleimide | tumor cell line, N-ethylmaleimide-sensitive | Mus musculus | |
| 3.1.4.1 | Zn2+ | - |
Bos taurus | |
| 3.1.4.1 | Zn2+ | tumor cell line, N-ethylmaleimide-sensitive | Homo sapiens | |
| 3.1.4.1 | Zn2+ | tumor cell line, N-ethylmaleimide-sensitive | Mus musculus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.1.4.1 | cytoplasm | tumor cell line, N-ethylmaleimide-sensitive | Mus musculus | 5737 | - |
| 3.1.4.1 | cytoplasm | tumor cell line, N-ethylmaleimide-sensitive | Homo sapiens | 5737 | - |
| 3.1.4.1 | cytoplasmic membrane | dithiothreitol-sensitive | Mus musculus | - |
- |
| 3.1.4.1 | cytoplasmic membrane | dithiothreitol-sensitive | Homo sapiens | - |
- |
| 3.1.4.1 | cytoplasmic membrane | dithiothreitol-sensitive | Bos taurus | - |
- |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.1 | 67000 | - |
tumor cell line, N-ethylmaleimide-sensitive, gel filtration and SDS-PAGE | Mus musculus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.4.1 | Bos taurus | - |
- |
- |
| 3.1.4.1 | Homo sapiens | - |
- |
- |
| 3.1.4.1 | Mus musculus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.4.1 | partial, liver | Mus musculus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.4.1 | Ehrlich ascites carcinoma cell | - |
Mus musculus | - |
| 3.1.4.1 | fibrosarcoma cell | Meth A tumor | Mus musculus | - |
| 3.1.4.1 | FM3A cell | - |
Mus musculus | - |
| 3.1.4.1 | HeLa cell | - |
Homo sapiens | - |
| 3.1.4.1 | hepatoma cell line | PLC/ PRF/5 human hepatoma | Homo sapiens | - |
| 3.1.4.1 | HL-60 cell | - |
Homo sapiens | - |
| 3.1.4.1 | intestine | dithiothreitol-sensitive | Bos taurus | - |
| 3.1.4.1 | K-562 cell | - |
Homo sapiens | - |
| 3.1.4.1 | KB cell | - |
Homo sapiens | - |
| 3.1.4.1 | L-1210 cell | - |
Mus musculus | - |
| 3.1.4.1 | liver | - |
Homo sapiens | - |
| 3.1.4.1 | liver | dithiothreitol-sensitive | Mus musculus | - |
| 3.1.4.1 | MH134 cell | - |
Mus musculus | - |
| 3.1.4.1 | MM46 cell | - |
Mus musculus | - |
| 3.1.4.1 | MOLT-3 cell | - |
Homo sapiens | - |
| 3.1.4.1 | myeloma cell line | murine mouse myeloma cell line P3-X63-Ag653 | Mus musculus | - |
| 3.1.4.1 | S-180 cell | - |
Mus musculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.4.1 | p-nitrophenylthymidine 5'-phosphate + H2O | - |
Mus musculus | 5'-TMP + p-nitrophenol | - |
? | |
| 3.1.4.1 | p-nitrophenylthymidine 5'-phosphate + H2O | - |
Homo sapiens | 5'-TMP + p-nitrophenol | - |
? | |
| 3.1.4.1 | p-nitrophenylthymidine 5'-phosphate + H2O | - |
Bos taurus | 5'-TMP + p-nitrophenol | - |
? | |
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