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Literature summary extracted from

  • Wilson, B.A.; Bantia, S.; Salituro, G.M.; Reeve, A.M.; Townsend, C.A.
    Cell-free biosynthesis of nocardicin A from nocardicin E and S-adenosylmethionine (1988), J. Am. Chem. Soc., 110, 8238-8239.
No PubMed abstract available

General Stability

EC Number General Stability Organism
2.5.1.38 partially purified enzyme is stable after dialysis against 50 mM phosphate buffer, pH 7.5, containing 20% glycerol and 10 mM 2-mercaptoethanol Nocardia uniformis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.38 S-adenosyl-L-methionine + nocardicin E Nocardia uniformis enzyme is involved in the biosynthesis of the beta-lactam antibiotic nocardicin A ?
-
 ?
5.1.1.14 Isonocardicin A Nocardia uniformis
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.38 Nocardia uniformis
-
 ssp. tsuyamanensis, ATCC 21806
-
5.1.1.14 Nocardia uniformis
-
 subs. tsyvamanensis ATCC 21806
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.38 ssp. tsuyamanensis, ATCC 21806, partial Nocardia uniformis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.38 S-adenosyl-L-methionine + nocardicin E
-
 Nocardia uniformis 5'-methylthioadenosine + isonocardicin A
-
 ?
2.5.1.38 S-adenosyl-L-methionine + nocardicin E enzyme is involved in the biosynthesis of the beta-lactam antibiotic nocardicin A Nocardia uniformis ?
-
 ?
5.1.1.14 Isonocardicin A the (9'S) configuration of isonocardicin A is converted into the (9'R) configuration Nocardia uniformis Nocardicin A
-
 ?
5.1.1.14 Isonocardicin A
-
 Nocardia uniformis ?
-
 ?