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Literature summary extracted from
- Purification of DNA ligases from mouse testis and their behavior during meiosis (1990), Cell Struct. Funct., 15, 67-72.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 6.5.1.1 | nucleus | - |
Mus musculus | 5634 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 6.5.1.1 | 65000 | - |
1 * 65000, DNA ligase II, SDS-PAGE | Mus musculus |
| 6.5.1.1 | 95000 | - |
1 * 95000, DNA ligase I, SDS-PAGE | Mus musculus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 6.5.1.1 | ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | Mus musculus | DNA ligase II might work at the final step of meiotic recombination reaction | ? | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 6.5.1.1 | Mus musculus | - |
DNA ligase I and II | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 6.5.1.1 | DNA ligase I and II | Mus musculus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 6.5.1.1 | bone marrow | - |
Mus musculus | - |
| 6.5.1.1 | liver | - |
Mus musculus | - |
| 6.5.1.1 | spermatocyte | highest activity | Mus musculus | - |
| 6.5.1.1 | spermatogonium | premeiotic, high activity | Mus musculus | - |
| 6.5.1.1 | testis | - |
Mus musculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 6.5.1.1 | ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | - |
Mus musculus | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? | |
| 6.5.1.1 | ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | DNA ligase II might work at the final step of meiotic recombination reaction | Mus musculus | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 6.5.1.1 | monomer | 1 * 95000, DNA ligase I, SDS-PAGE | Mus musculus |
| 6.5.1.1 | monomer | 1 * 65000, DNA ligase II, SDS-PAGE | Mus musculus |
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Release 2023.1 (January 2023)
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