Literature summary extracted from

Li, C.; Cao, L.G.; Wang, Y.L.; Baril, E.F.
Further purification and characterization of a multienzyme complex for DNA synthesis in human cells (1993), J. Cell. Biochem., 53, 405-419.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
6.5.1.1	nucleus	localized to granular-like foci within the nucleus during S-phase	Homo sapiens	5634	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
6.5.1.1	Homo sapiens	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
6.5.1.1	multienzyme complex consisting of DNA polymerase alpha-primase, a 3',5'-exonuclease, DNA ligase I, RNase H, and topoisomerase I	Homo sapiens

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6.5.1.1	ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m	-	Homo sapiens	AMP + diphosphate + (deoxyribonucleotide)n+m	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)