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Literature summary extracted from

  • Yang, S.; Becker, F.F.; Chan, J.Y.H.
    Biochemical characterization of a protein inhibitor for DNA ligase I from human cells (1993), Biochem. Biophys. Res. Commun., 191, 1004-1013.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.5.1.1 Protein inhibitor inhibitor protein purified from human cells, MW 55000-75000, forms a reversible complex with DNA ligase I, but has no effect on DNA ligase II. The inhibitor may play a regulatory role for DNA replication and repair Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
6.5.1.1 Homo sapiens
-
-
-
6.5.1.1 Tequatrovirus T4
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.5.1.1 ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
-
 Homo sapiens AMP + diphosphate + (deoxyribonucleotide)n+m
-
 ?
6.5.1.1 ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
-
 Tequatrovirus T4 AMP + diphosphate + (deoxyribonucleotide)n+m
-
 ?