EC Number | Cloned (Comment) | Organism |
---|---|---|
6.5.1.1 | - |
Saccharomyces cerevisiae |
6.5.1.1 | - |
Schizosaccharomyces pombe |
6.5.1.1 | - |
Vaccinia virus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.5.1.1 | 0.00004 | - |
DNA | nicked DNA, enzyme DNA ligase II | Bos taurus | |
6.5.1.1 | 0.00011 | - |
DNA | nicked DNA, enzyme DNA ligase I | Bos taurus | |
6.5.1.1 | 0.001 | - |
ATP | - |
Drosophila melanogaster | |
6.5.1.1 | 0.002 | - |
ATP | DNA ligase I | Bos taurus | |
6.5.1.1 | 0.002 | - |
ATP | ATP, ATP-diphosphate exchange reaction | Bos taurus | |
6.5.1.1 | 0.04 | - |
ATP | DNA ligase II | Bos taurus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
6.5.1.1 | nucleus | - |
Drosophila melanogaster | 5634 | - |
6.5.1.1 | nucleus | - |
Mammalia | 5634 | - |
6.5.1.1 | nucleus | DNA ligase II is more firmly retained in isolated cell nuclei than DNA ligase I | Bos taurus | 5634 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
6.5.1.1 | 85000 | - |
x * 85000, calculation from nucleotide sequence, SDS-PAGE | Saccharomyces cerevisiae |
6.5.1.1 | 86000 | - |
x * 86000, calculation from nucleotide sequence, SDS-PAGE | Schizosaccharomyces pombe |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.5.1.1 | Bos taurus | - |
calf | - |
6.5.1.1 | Drosophila melanogaster | - |
DNA ligase I and II | - |
6.5.1.1 | Mammalia | - |
- |
- |
6.5.1.1 | Saccharomyces cerevisiae | - |
- |
- |
6.5.1.1 | Schizosaccharomyces pombe | - |
- |
- |
6.5.1.1 | Vaccinia virus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
6.5.1.1 | DNA ligase I and II | Mammalia |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
6.5.1.1 | embryo | - |
Drosophila melanogaster | - |
6.5.1.1 | thymus | - |
Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.5.1.1 | ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | can join a 3'-hydroxyl terminus of DNA to a 5'-hydroxyl terminus of RNA, can join oligo(rA)12*poly(dT), blunt end joining in presence of polyethylene glycol | Drosophila melanogaster | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? | |
6.5.1.1 | ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | inability to ligate oligo(dT)*poly(rA) | Drosophila melanogaster | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? | |
6.5.1.1 | ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | inability to ligate oligo(dT)*poly(rA) | Mammalia | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? | |
6.5.1.1 | ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | inability to ligate oligo(dT)*poly(rA) | Saccharomyces cerevisiae | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? | |
6.5.1.1 | ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | inability to ligate oligo(dT)*poly(rA) | Bos taurus | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? | |
6.5.1.1 | ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | inability to ligate oligo(dT)*poly(rA) | Schizosaccharomyces pombe | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? | |
6.5.1.1 | ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | inability to ligate oligo(dT)*poly(rA) | Vaccinia virus | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? | |
6.5.1.1 | ATP + DNA | - |
Bos taurus | AMP + diphosphate + ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
6.5.1.1 | ? | - |
Drosophila melanogaster |
6.5.1.1 | ? | x * 120000-130000, SDS-PAGE, gel filtration under denaturing conditions, DNA ligase I | Bos taurus |
6.5.1.1 | ? | x * 85000, calculation from nucleotide sequence, SDS-PAGE | Saccharomyces cerevisiae |
6.5.1.1 | ? | x * 86000, calculation from nucleotide sequence, SDS-PAGE | Schizosaccharomyces pombe |