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Literature summary extracted from

  • Barden, R.E.; Taylor, B.L.; Isohashi, F.; Frey, W.H.; Zander, G.; Lee, J.C.; Utter, M.F.
    Structural properties of pyruvate carboxylase from chicken liver and other sources (1975), Proc. Natl. Acad. Sci. USA, 72, 4308-4312.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.4.1.1 12000
-
 4 * 12000, SDS-PAGE Bos taurus
6.4.1.1 54000
-
 2 * 65000 + 2 * 54000, SDS-PAGE Pseudomonas citronellolis
6.4.1.1 65000
-
 2 * 65000 + 2 * 54000, SDS-PAGE Pseudomonas citronellolis
6.4.1.1 110000
-
 4 * 110000, SDS-PAGE Meleagris gallopavo
6.4.1.1 125000
-
 4 * 125000, SDS-PAGE Gallus gallus
6.4.1.1 125000
-
 4 * 125000, SDS-PAGE Saccharomyces cerevisiae
6.4.1.1 130000
-
 4 * 130000, SDS-PAGE Homo sapiens
6.4.1.1 130000
-
 4 * 130000, SDS-PAGE Rattus norvegicus
6.4.1.1 130000
-
 4 * 130000, SDS-PAGE Sus scrofa
6.4.1.1 475000
-
 meniscus depletion sedimentation equilibrium method Saccharomyces cerevisiae
6.4.1.1 500000
-
 approach to equilibrium ultracentrifugation Gallus gallus
6.4.1.1 500000
-
 approach to equilibrium ultracentrifugation Meleagris gallopavo
6.4.1.1 500000
-
 approach to equilibrium ultracentrifugation Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
6.4.1.1 Bos taurus
-
 calf
-
6.4.1.1 Gallus gallus
-
-
-
6.4.1.1 Homo sapiens
-
-
-
6.4.1.1 Meleagris gallopavo
-
-
-
6.4.1.1 Pseudomonas citronellolis
-
-
-
6.4.1.1 Rattus norvegicus
-
-
-
6.4.1.1 Saccharomyces cerevisiae
-
-
-
6.4.1.1 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.4.1.1 liver
-
 Gallus gallus
-
6.4.1.1 liver
-
 Meleagris gallopavo
-
6.4.1.1 liver
-
 Homo sapiens
-
6.4.1.1 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.4.1.1 ATP + pyruvate + HCO3-
-
 Gallus gallus ADP + phosphate + oxaloacetate
-
 ?
6.4.1.1 ATP + pyruvate + HCO3-
-
 Meleagris gallopavo ADP + phosphate + oxaloacetate
-
 ?
6.4.1.1 ATP + pyruvate + HCO3-
-
 Homo sapiens ADP + phosphate + oxaloacetate
-
 ?
6.4.1.1 ATP + pyruvate + HCO3-
-
 Rattus norvegicus ADP + phosphate + oxaloacetate
-
 ?
6.4.1.1 ATP + pyruvate + HCO3-
-
 Sus scrofa ADP + phosphate + oxaloacetate
-
 ?
6.4.1.1 ATP + pyruvate + HCO3-
-
 Saccharomyces cerevisiae ADP + phosphate + oxaloacetate
-
 ?
6.4.1.1 ATP + pyruvate + HCO3-
-
 Bos taurus ADP + phosphate + oxaloacetate
-
 ?
6.4.1.1 ATP + pyruvate + HCO3-
-
 Pseudomonas citronellolis ADP + phosphate + oxaloacetate
-
 ?

Subunits

EC Number Subunits Comment Organism
6.4.1.1 tetramer 4 * 130000, SDS-PAGE Homo sapiens
6.4.1.1 tetramer 4 * 130000, SDS-PAGE Rattus norvegicus
6.4.1.1 tetramer 4 * 130000, SDS-PAGE Sus scrofa
6.4.1.1 tetramer 2 * 65000 + 2 * 54000, SDS-PAGE Pseudomonas citronellolis
6.4.1.1 tetramer 4 * 125000, SDS-PAGE Gallus gallus
6.4.1.1 tetramer 4 * 125000, SDS-PAGE Saccharomyces cerevisiae
6.4.1.1 tetramer 4 * 110000, SDS-PAGE Meleagris gallopavo
6.4.1.1 tetramer 4 * 12000, SDS-PAGE Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
6.4.1.1 biotin enzyme contains biotin Gallus gallus
6.4.1.1 biotin enzyme contains biotin Homo sapiens
6.4.1.1 biotin enzyme contains biotin Rattus norvegicus
6.4.1.1 biotin enzyme contains biotin Pseudomonas citronellolis