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Literature summary extracted from

  • Greenberg, D.M.
    Arginase (1960), The Enzymes, 2nd Ed. (Boyer, P. D. , Lardy, H. , Myrbäck, K. , eds. ), 4, 257-267.
No PubMed abstract available

General Stability

EC Number General Stability Organism
3.5.3.1 unstable at high dilution, ornithine or glycine stabilize Mammalia

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.3.1 Ag+
-
 Mammalia
3.5.3.1 Borate buffer Mammalia
3.5.3.1 citrate buffer Mammalia
3.5.3.1 Hg2+
-
 Mammalia
3.5.3.1 L-lysine
-
 Mammalia
3.5.3.1 L-ornithine
-
 Mammalia
3.5.3.1 Zn2+
-
 Mammalia

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.5.3.1 Co2+ activating Mammalia
3.5.3.1 Mn2+ activating Mammalia

Organism

EC Number Organism UniProt Comment Textmining
3.5.3.1 Mammalia
-
 overview
-

Storage Stability

EC Number Storage Stability Organism
3.5.3.1 4°C, aqueous solutions, pH 7 Mammalia

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.3.1 argininic acid + H2O
-
 Mammalia urea + 5-amino-2-hydroxypentanoate
-
 ?
3.5.3.1 L-arginine + H2O
-
 Mammalia L-ornithine + urea
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.5.3.1 additional information
-
 metal ions protect from heat inactivation Mammalia

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.5.3.1 2200
-
 L-Arg
-
 Mammalia

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.3.1 7
-
 with Co2+ and Ni2+ Mammalia

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
3.5.3.1 6 9 below pH 6.0 and above 9.0 rapid loss of activity Mammalia