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Literature summary extracted from
- The bacterial degradation of pantothenic acid. II. pantothenate hydrolase (1966), Biochemistry, 5, 399-403.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.5.1.22 | dieethyldithiocarbamate | 10 mM, 36% inhibition | Pseudomonas fluorescens |  |
| 3.5.1.22 | EDTA | 10 mM, 45% inhibition | Pseudomonas fluorescens | |
| 3.5.1.22 | KCN | 10 mM, 42% inhibition | Pseudomonas fluorescens | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.5.1.22 | 5 | - |
pantothenic acid | P-2, pH 7.4 at 28°C | Pseudomonas fluorescens | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.1.22 | pantothenic acid + H2O | Pseudomonas fluorescens | - |
? | - |
? | |
| 3.5.1.22 | pantothenic acid + H2O | Pseudomonas fluorescens P-2 | - |
? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.1.22 | Pseudomonas fluorescens | - |
P-2 | - |
| 3.5.1.22 | Pseudomonas fluorescens P-2 | - |
P-2 | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.5.1.22 | - |
Pseudomonas fluorescens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.1.22 | pantothenic acid + H2O | - |
Pseudomonas fluorescens | beta-alanine + D-pantoyl lactone + H2O | - |
r | |
| 3.5.1.22 | pantothenic acid + H2O | - |
Pseudomonas fluorescens P-2 | beta-alanine + D-pantoyl lactone + H2O | - |
r | |
| 3.5.1.22 | pantothenic acid + H2O | - |
Pseudomonas fluorescens | ? | - |
? | |
| 3.5.1.22 | pantothenic acid + H2O | - |
Pseudomonas fluorescens P-2 | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.5.1.22 | pantothenate hydrolase | - |
Pseudomonas fluorescens |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.5.1.22 | 28 | 29 | above 30°C denaturation of enzyme | Pseudomonas fluorescens |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.5.1.22 | 7.4 | - |
strain P-2 | Pseudomonas fluorescens |
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