Literature summary extracted from

Pomponio,R.J.; Reynolds, T.R.; Cole, H.; Buck, G.A.; Wolf, B.
Mutational hotspot in the human biotinidase gene causes profound biotinidase deficiency (1995), Nature Genet., 11, 96-98.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
3.5.1.12	PCR amplification mutational hotspot in biotinidase gene identified, causes biotinidase deficiency, located on chromosome 3p25	Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.5.1.12	biotin amide + H2O	Homo sapiens	-	?	-	?
3.5.1.12	epsilon-N-biotinyl-L-lysine + H2O	Homo sapiens	-	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.5.1.12	Homo sapiens	-	human	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.5.1.12	biotin amide + H2O	-	Homo sapiens	?	-	?
3.5.1.12	epsilon-N-biotinyl-L-lysine + H2O	-	Homo sapiens	biotin + L-lysine	-	ir
3.5.1.12	epsilon-N-biotinyl-L-lysine + H2O	-	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)