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Literature summary extracted from

  • Cutruzzola, F.; Ascenzi, P.; Barra, D.; Bolognesi, M.; Menegatti, E.; Sarti, P.; Schnebli, H.P.; Tomova, S.; Amiconi, G.
    Selective oxidation of Met-192 in bovine alpha-chymotrypsin. Effect on catalytic and inhibitor binding properties (1993), Biochim. Biophys. Acta, 1161, 201-208.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
3.4.21.1 additional information selective oxidation of Met192 to its sulfoxide derivative leads to changes of catalytic parameters for the hydrolysis of synthetic substrates and thermodynamic and kinetic interactions with the macromolecular inhibitor eglin c Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.1 bovine basic panreatic trypsin inhibitor
-
 Bos taurus
3.4.21.1 Eglin c
-
 Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.1 Bos taurus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.1 Nalpha-benzyloxycarbonyl-L-Ala p-nitrophenyl ester + H2O
-
 Bos taurus Nalpha-benzyloxycarbonyl-L-Ala + p-nitrophenol
-
 ?
3.4.21.1 Nalpha-benzyloxycarbonyl-L-Leu p-nitrophenyl ester + H2O
-
 Bos taurus Nalpha-benzyloxycarbonyl-L-Leu + p-nitrophenol
-
 ?
3.4.21.1 Nalpha-benzyloxycarbonyl-L-Lys p-nitrophenyl ester + H2O
-
 Bos taurus Nalpha-benzyloxycarbonyl-L-Lys + p-nitrophenol
-
 ?
3.4.21.1 Nalpha-benzyloxycarbonyl-L-Tyr p-nitrophenyl ester + H2O
-
 Bos taurus Nalpha-benzyloxycarbonyl-L-Tyr + p-nitrophenol
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.21.1 additional information
-
 additional information
-
 Bos taurus