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Literature summary extracted from

  • Ascenzi, P.; Menegatti, E.; Guarneri, M.; Bortolotti, F.; Antonini, E.
    Catalytic properties of serine proteases. 2. Comparison between human urinary kallikrein and human urokinase, bovine beta-trypsin, bovine thrombin, and bovine alpha-chymotrypsin (1982), Biochemistry, 21, 2483-2490.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.1 benzamidine
-
 Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.21.1 0.08
-
 Nalpha-benzyloxycarbonyl-L-Tyr p-nitrophenyl ester
-
 Bos taurus
3.4.21.1 0.09
-
 Nalpha-benzyloxycarbonyl-L-Ala p-nitrophenyl ester at pH 6.0 Bos taurus
3.4.21.1 0.1
-
 Nalpha-benzyloxycarbonyl-L-Ala p-nitrophenyl ester at pH 4.0 Bos taurus
3.4.21.1 0.4
-
 Nalpha-tosyl-L-Tyr benzyl ester
-
 Bos taurus
3.4.21.1 0.62
-
 Nalpha-benzyloxycarbonyl-L-Lys p-nitrophenyl ester at pH 6.0 Bos taurus
3.4.21.1 0.64
-
 Nalpha-benzyloxycarbonyl-L-Lys p-nitrophenyl ester at pH 4.0 Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.1 Bos taurus
-
 alpha-chymotrypsin
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.1 Nalpha-benzyloxycarbonyl-L-Ala p-nitrophenyl ester + H2O
-
 Bos taurus Nalpha-benzyloxycarbonyl-L-Ala + p-nitrophenol
-
 ?
3.4.21.1 Nalpha-benzyloxycarbonyl-L-Lys p-nitrophenyl ester + H2O
-
 Bos taurus Nalpha-benzyloxycarbonyl-L-Lys + p-nitrophenol
-
 ?
3.4.21.1 Nalpha-benzyloxycarbonyl-L-Tyr p-nitrophenyl ester + H2O
-
 Bos taurus Nalpha-benzyloxycarbonyl-L-Tyr + p-nitrophenol
-
 ?
3.4.21.1 Nalpha-tosyl-L-Tyr benzyl ester + H2O
-
 Bos taurus Nalpha-tosyl-L-Tyr + phenol
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.21.1 0.008
-
 Nalpha-benzyloxycarbonyl-L-Ala p-nitrophenyl ester at pH 4.0 Bos taurus
3.4.21.1 0.3
-
 Nalpha-benzyloxycarbonyl-L-Ala p-nitrophenyl ester at pH 6.0 Bos taurus
3.4.21.1 0.6
-
 Nalpha-benzyloxycarbonyl-L-Lys p-nitrophenyl ester at pH 4.0 Bos taurus
3.4.21.1 6.43
-
 Nalpha-benzyloxycarbonyl-L-Ala p-nitrophenyl ester at pH 6.0 Bos taurus
3.4.21.1 21.4
-
 Nalpha-tosyl-L-Tyr benzyl ester
-
 Bos taurus
3.4.21.1 85
-
 Nalpha-benzyloxycarbonyl-L-Tyr p-nitrophenyl ester
-
 Bos taurus