Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Dianov, G.; Lindahl, T.
    Preferential recognition of I-T base-pairs in the initiation of excision-repair by hypoxanthine-DNA glycosylase (1991), Nucleic Acids Res., 19, 3829-3833.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.2.15 nucleus
-
 Homo sapiens 5634
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.2.15 30000
-
-
 Escherichia coli
3.2.2.15 31000
-
 SDS-PAGE Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.2.2.15 Bos taurus
-
 calf
-
3.2.2.15 Escherichia coli
-
-
-
3.2.2.15 Homo sapiens
-
 HeLa cells
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.2.15
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.2.15 skin fibroblast
-
 Bos taurus
-
3.2.2.15 skin fibroblast HeLa cells nuclear extract Homo sapiens
-
3.2.2.15 thymus
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.2.15 DNA + H2O preference for double-stranded substrates Bos taurus hypoxanthine + ?
-
 ?
3.2.2.15 additional information
-
 Escherichia coli ?
-
 ?
3.2.2.15 additional information
-
 Homo sapiens ?
-
 ?
3.2.2.15 additional information no detectable enzyme activity on double-stranded oligonucleotides containing mismatched base pairs Bos taurus ?
-
 ?
3.2.2.15 polydeoxynucleotides + H2O
-
 Escherichia coli hypoxanthine + ?
-
 ?
3.2.2.15 polydeoxynucleotides + H2O synthetic oligonucleotides Bos taurus hypoxanthine + ? cleaves the dIMP residue into free hypoxanthine and a deoxyribosephosphate residue remaining in DNA ?