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Literature summary extracted from

  • Rome, L.H.
    alpha-L-Iduronidase from human kidney (1982), Methods Enzymol., 83, 578-583.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.2.1.76 2-mercaptoethanol
-
Homo sapiens
3.2.1.76 dithiothreitol
-
Homo sapiens
3.2.1.76 glutathione
-
Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.76 p-chloromercuribenzoate
-
Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.76 0.09
-
4-methylumbelliferyl-alpha-L-iduronide
-
Homo sapiens
3.2.1.76 1.5
-
phenyl alpha-L-iduronide
-
Homo sapiens
3.2.1.76 9
-
anhydromannitol iduronide
-
Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.1.76 60000
-
sedimentation equilibrium Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.76 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.2.1.76 glycoprotein
-
Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.76
-
Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.76 kidney
-
Homo sapiens
-
3.2.1.76 urine
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.2.1.76 250
-
-
Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.76 phenyl alpha-L-iduronide + H2O
-
Homo sapiens ?
-
?

Subunits

EC Number Subunits Comment Organism
3.2.1.76 dimer
-
Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.76 4
-
-
Homo sapiens
3.2.1.76 4.5
-
anhydromannitol as substrate Homo sapiens