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Literature summary extracted from

  • Sting, R.; Schaufuss, P.; Blobel, H.
    Isolation and characterization of hyaluronidases from Streptococcus dysgalactiae, S. zooepidemicus and S. equi (1990), Zentralbl. Bakteriol., 272, 276-282.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.35 Cd2+
-
 Streptococcus dysgalactiae
3.2.1.35 Zn2+
-
 Streptococcus dysgalactiae
3.2.1.36 Cd2+
-
 Streptococcus equinus
3.2.1.36 Cd2+
-
 Streptococcus equi subsp. zooepidemicus
3.2.1.36 Zn2+
-
 Streptococcus equinus
3.2.1.36 Zn2+
-
 Streptococcus equi subsp. zooepidemicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.1.35 extracellular secreted from cell culture Streptococcus dysgalactiae
-
-
3.2.1.36 extracellular secreted from cell culture Streptococcus equinus
-
-
3.2.1.36 extracellular secreted from cell culture Streptococcus equi subsp. zooepidemicus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.2.1.35 Ca2+
-
 Streptococcus dysgalactiae
3.2.1.35 Co2+
-
 Streptococcus dysgalactiae
3.2.1.35 K+
-
 Streptococcus dysgalactiae
3.2.1.35 Li+
-
 Streptococcus dysgalactiae
3.2.1.35 Mg2+
-
 Streptococcus dysgalactiae
3.2.1.35 Mn2+
-
 Streptococcus dysgalactiae
3.2.1.36 Ca2+
-
 Streptococcus equinus
3.2.1.36 Ca2+
-
 Streptococcus equi subsp. zooepidemicus
3.2.1.36 Co2+
-
 Streptococcus equinus
3.2.1.36 Co2+
-
 Streptococcus equi subsp. zooepidemicus
3.2.1.36 K+
-
 Streptococcus equinus
3.2.1.36 K+
-
 Streptococcus equi subsp. zooepidemicus
3.2.1.36 Li+
-
 Streptococcus equinus
3.2.1.36 Li+
-
 Streptococcus equi subsp. zooepidemicus
3.2.1.36 Mg2+
-
 Streptococcus equinus
3.2.1.36 Mg2+
-
 Streptococcus equi subsp. zooepidemicus
3.2.1.36 Mn2+
-
 Streptococcus equinus
3.2.1.36 Mn2+
-
 Streptococcus equi subsp. zooepidemicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.1.35 55000
-
 SDS-PAGE Streptococcus dysgalactiae
3.2.1.36 55000
-
 SDS-PAGE Streptococcus equinus
3.2.1.36 55000
-
 SDS-PAGE Streptococcus equi subsp. zooepidemicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.35 hyaluronic acid + H2O Streptococcus dysgalactiae
-
 ?
-
 ?
3.2.1.36 hyaluronic acid + H2O Streptococcus equinus
-
 ?
-
 ?
3.2.1.36 hyaluronic acid + H2O Streptococcus equi subsp. zooepidemicus
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.35 Streptococcus dysgalactiae
-
-
-
3.2.1.36 Streptococcus equi subsp. zooepidemicus
-
-
-
3.2.1.36 Streptococcus equinus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.35 to homogeneity, chromatography, isoelectric focusing Streptococcus dysgalactiae
3.2.1.36 to homogeneity, chromatography steps, isoelectric focusing Streptococcus equinus
3.2.1.36 to homogeneity, chromatography steps, isoelectric focusing Streptococcus equi subsp. zooepidemicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.35 cell culture
-
 Streptococcus dysgalactiae
-
3.2.1.36 cell culture
-
 Streptococcus equinus
-
3.2.1.36 cell culture
-
 Streptococcus equi subsp. zooepidemicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.35 hyaluronic acid + H2O
-
 Streptococcus dysgalactiae ?
-
 ?
3.2.1.35 hyaluronic acid + H2O
-
 Streptococcus dysgalactiae hyaluronic acid oligomers
-
 ?
3.2.1.36 hyaluronic acid + H2O
-
 Streptococcus equinus ?
-
 ?
3.2.1.36 hyaluronic acid + H2O
-
 Streptococcus equi subsp. zooepidemicus ?
-
 ?
3.2.1.36 hyaluronic acid + H2O
-
 Streptococcus equinus hyaluronic acid oligomers
-
 ?
3.2.1.36 hyaluronic acid + H2O
-
 Streptococcus equi subsp. zooepidemicus hyaluronic acid oligomers
-
 ?

Subunits

EC Number Subunits Comment Organism
3.2.1.35 monomer 1 * 55000, SDS-PAGE Streptococcus dysgalactiae
3.2.1.36 monomer 1 * 55000, SDS-PAGE Streptococcus equinus
3.2.1.36 monomer 1 * 55000, SDS-PAGE Streptococcus equi subsp. zooepidemicus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.2.1.35 40 45
-
 Streptococcus dysgalactiae
3.2.1.36 40 45
-
 Streptococcus equinus
3.2.1.36 40 45
-
 Streptococcus equi subsp. zooepidemicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.35 5.6 5.8
-
 Streptococcus dysgalactiae
3.2.1.36 5.6 5.8
-
 Streptococcus equinus
3.2.1.36 5.6 5.8
-
 Streptococcus equi subsp. zooepidemicus