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Literature summary extracted from

  • Ozegowski, J.H.; Gunther, E.; Reichardt, W.
    Purification and characterization of hyaluronidase from Streptococcus agalactiae (1994), Zentralbl. Bakteriol., 280, 497-506.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.36 Al3+ strong inhibition at 10 mM Streptococcus agalactiae
3.2.1.36 Cu2+ nearly complete inhibition at 10 mM Streptococcus agalactiae
3.2.1.36 Fe2+ complete inhibition at 10 mM Streptococcus agalactiae
3.2.1.36 Mn2+ strong inhibition at 10 mM Streptococcus agalactiae
3.2.1.36 polymer from gentisic acid with formaldehyde, nearly complete inhibition at 0.01 mg/ml Streptococcus agalactiae
3.2.1.36 polymer from hydroxysulfonic acid with formaldehyde, nearly complete inhibition at 0.01 mg/ml Streptococcus agalactiae
3.2.1.36 Zn2+ strong inhibition at 10 mM Streptococcus agalactiae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.36 additional information
-
hyaluronoic acid value in mg/ml Streptococcus agalactiae
3.2.1.36 additional information
-
hyaluronoic acid 0.08 mg/ml Streptococcus agalactiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.1.36 extracellular secreted from cell culture Streptococcus agalactiae
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.2.1.36 Mg2+ 4fold increased activity at 10 mM Streptococcus agalactiae

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.1.36 116000
-
SDS-PAGE Streptococcus agalactiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.36 hyaluronic acid + H2O Streptococcus agalactiae major pathogenic factor of serological group B streptococci ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.36 Streptococcus agalactiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.36 highly purified, chromatography steps Streptococcus agalactiae

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.36 cell culture serological group B strains, 3402 type II and 4755 Streptococcus agalactiae
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.2.1.36 additional information
-
activity measured as turbidicity reducing units Streptococcus agalactiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.36 chondroitin sulfate A + H2O low activity Streptococcus agalactiae oligosaccharides + ?
-
?
3.2.1.36 dermatan sulfate + H2O chondroitin sulfate B, low activity Streptococcus agalactiae ?
-
?
3.2.1.36 hyaluronic acid + H2O major pathogenic factor of serological group B streptococci Streptococcus agalactiae ?
-
?
3.2.1.36 hyaluronic acid + H2O
-
Streptococcus agalactiae hyaluronic acid oligomers
-
?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.36 6.3
-
-
Streptococcus agalactiae