Any feedback?
Literature summary extracted from
- Purification and properties of cloned Salmonella typhimurium LT2 sialidase with virus-typical kinetic preference for sialyl alpha2-3 linkages (1991), J. Biochem., 110, 462-467.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.2.1.18 | overproduction in Escherichia coli | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.2.1.18 | 2-Deoxy-2,3-didehydro-N-acetylneuraminic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 |  |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.2.1.18 | 0.25 | - |
4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.2.1.18 | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.2.1.18 | - |
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.2.1.18 | 3.9 | - |
- |
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.1.18 | 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | 4-methylumbelliferone + alpha-D-N-acetylneuraminic acid | - |
? | |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.2.1.18 | 45 | - |
4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid | - |
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.2.1.18 | 5.5 | 7 | - |
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
