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Literature summary extracted from

  • Thomas, G.H.; Reynolds, L.W.; Miller, C.S.
    Characterization of neuraminidase activity of cultured human fibroblasts (1979), Biochim. Biophys. Acta, 568, 39-48.
    View publication on PubMed

General Stability

EC Number General Stability Organism
3.2.1.18 labile towards freezing and thrawing Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.18 0.36
-
 fetuin
-
 Homo sapiens
3.2.1.18 1.1
-
 2-(3-methoxyphenyl)-N-acetylneuraminic acid
-
 Homo sapiens
3.2.1.18 3
-
 N-acetylneuraminyllactose
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.18 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.18 fibroblast
-
 Homo sapiens
-

Storage Stability

EC Number Storage Stability Organism
3.2.1.18 -70°C, after 48 h inactivated Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.18 2-(3-methoxyphenyl)-N-acetylneuraminic acid + H2O
-
 Homo sapiens 3-methoxyphenol + N-acetylneuraminic acid
-
 ?
3.2.1.18 fetuin + H2O
-
 Homo sapiens ?
-
 ?
3.2.1.18 N-acetylneuraminyllactose + H2O
-
 Homo sapiens N-acetylneuraminic acid + lactose
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.2.1.18 52
-
 inactivated Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.18 4.2 4.6
-
 Homo sapiens