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Literature summary extracted from

  • Teufel, M.; Roggentin, P.; Schauer, R.
    Properties of sialidase isolated from Actinomyces viscosus DSM 43798 (1989), Biol. Chem. Hoppe-Seyler, 370, 435-443.
    View publication on PubMed

General Stability

EC Number General Stability Organism
3.2.1.18 labile towards freezing and thrawing Actinomyces viscosus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.18 2-Deoxy-2,3-didehydro-N-acetylneuraminic acid
-
 Actinomyces viscosus
3.2.1.18 Hg2+
-
 Actinomyces viscosus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.18 0.1
-
 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid
-
 Actinomyces viscosus
3.2.1.18 3.3
-
 sialyl-alpha-2,6-lactose
-
 Actinomyces viscosus
3.2.1.18 4.9
-
 sialyl-alpha-2,3-lactose
-
 Actinomyces viscosus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.1.18 cell associated
-
 Actinomyces viscosus
-
-
3.2.1.18 extracellular
-
 Actinomyces viscosus
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.1.18 180000
-
 gel filtration Actinomyces viscosus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.18 alpha1-acid glycoprotein + H2O Actinomyces viscosus
-
 ?
-
 ?
3.2.1.18 colominic acid + H2O Actinomyces viscosus
-
 ?
-
 ?
3.2.1.18 fetuin + H2O Actinomyces viscosus
-
 ?
-
 ?
3.2.1.18 ganglioside GD1a + H2O Actinomyces viscosus
-
 ?
-
 ?
3.2.1.18 N-acetylneuraminic acid-alpha-2,3-lactose + H2O Actinomyces viscosus
-
 ?
-
 ?
3.2.1.18 N-acetylneuraminic acid-alpha-2,6-lactose + H2O Actinomyces viscosus
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.18 Actinomyces viscosus
-
 DSM 43798
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.18
-
 Actinomyces viscosus

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.2.1.18 680
-
-
 Actinomyces viscosus

Storage Stability

EC Number Storage Stability Organism
3.2.1.18 4°C, 0.1 M acetate buffer, pH 5 Actinomyces viscosus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.18 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid + H2O
-
 Actinomyces viscosus 4-methylumbelliferone + N-acetylneuraminic acid
-
 ?
3.2.1.18 alpha1-acid glycoprotein + H2O
-
 Actinomyces viscosus ?
-
 ?
3.2.1.18 colominic acid + H2O
-
 Actinomyces viscosus ?
-
 ?
3.2.1.18 fetuin + H2O
-
 Actinomyces viscosus ?
-
 ?
3.2.1.18 ganglioside GD1a + H2O
-
 Actinomyces viscosus ?
-
 ?
3.2.1.18 N-acetylneuraminic acid-alpha-2,3-lactose + H2O
-
 Actinomyces viscosus N-acetylneuraminic acid + lactose
-
 ?
3.2.1.18 N-acetylneuraminic acid-alpha-2,3-lactose + H2O
-
 Actinomyces viscosus ?
-
 ?
3.2.1.18 N-acetylneuraminic acid-alpha-2,6-lactose + H2O
-
 Actinomyces viscosus N-acetylneuraminic acid + lactose
-
 ?
3.2.1.18 N-acetylneuraminic acid-alpha-2,6-lactose + H2O
-
 Actinomyces viscosus ?
-
 ?
3.2.1.18 sialyl-alpha-2,3-lactose + H2O
-
 Actinomyces viscosus ?
-
 ?
3.2.1.18 sialyl-alpha-2,6-lactose + H2O
-
 Actinomyces viscosus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.2.1.18 monomer SDS-PAGE Actinomyces viscosus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.2.1.18 37
-
-
 Actinomyces viscosus

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
3.2.1.18 10 60
-
 Actinomyces viscosus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.18 5
-
-
 Actinomyces viscosus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.2.1.18 3 6
-
 Actinomyces viscosus