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Literature summary extracted from

  • Mori, M.; Hosokawa, M.; Ogasawara, Y.; Tsukada, E.; Chiba, K.
    cDNA cloning, characterization and stable expression of a novel human brain carboxylesterase (1999), FEBS Lett., 458, 17-22.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.1
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.1 0.0229
-
 4-nitrophenyl acetate isoenzyme hBr3/pTARGET Homo sapiens
3.1.1.1 0.365
-
 4-nitrophenyl acetate isoenzyme HU1/pTARGET Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.1 additional information Homo sapiens the enzyme may function as a blood-brain barrier to protect the central nervous system from ester or amide compounds ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.1 Homo sapiens P23141 isoenzyme hBr3/pTARGET and HU1/pTARGET
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.1 brain
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.1 4-nitrophenyl acetate + H2O
-
 Homo sapiens 4-nitrophenol + acetate
-
 ?
3.1.1.1 additional information the enzyme may function as a blood-brain barrier to protect the central nervous system from ester or amide compounds Homo sapiens ?
-
 ?
3.1.1.1 oleoyl-CoA + H2O
-
 Homo sapiens oleic acid + CoA
-
 ?
3.1.1.1 palmitoyl-CoA + H2O weak Homo sapiens palmitic acid + CoA
-
 ?
3.1.1.1 temocapril + H2O weak Homo sapiens ?
-
 ?