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Literature summary extracted from

  • Houston, L.L.; Graham, M.E.
    Divalent metal Ion effects on a mutant histidinol phophate phosphatase from Samonella typhimurium (1974), Arch. Biochem. Biophys., 162, 513-522.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.15 Be2+
-
 Salmonella enterica subsp. enterica serovar Typhimurium
3.1.3.15 Ca2+
-
 Salmonella enterica subsp. enterica serovar Typhimurium
3.1.3.15 Mg2+
-
 Salmonella enterica subsp. enterica serovar Typhimurium
3.1.3.15 Ni2+
-
 Salmonella enterica subsp. enterica serovar Typhimurium

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.3.15 0.1 0.3 L-histidinol phosphate
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.15 Be2+ increases Km at pH 6.5 Salmonella enterica subsp. enterica serovar Typhimurium
3.1.3.15 Co2+ shifts optimal pH to 6.5, decreases Km at pH 6.5 Salmonella enterica subsp. enterica serovar Typhimurium
3.1.3.15 Fe2+ decreases Km at pH 6.5 Salmonella enterica subsp. enterica serovar Typhimurium
3.1.3.15 Mg2+ shifts optimal pH to 6.5 Salmonella enterica subsp. enterica serovar Typhimurium
3.1.3.15 Mn2+ shifts optimal pH to 6.5, decreases Km at pH 6.5 Salmonella enterica subsp. enterica serovar Typhimurium
3.1.3.15 Ni2+ increases Km at pH 6.5 Salmonella enterica subsp. enterica serovar Typhimurium
3.1.3.15 Zn2+ shifts optimal pH to 6.5, decreases Km at pH 6.5 Salmonella enterica subsp. enterica serovar Typhimurium

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.15 52000
-
 disc gel electrophoresis Salmonella enterica subsp. enterica serovar Typhimurium

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.15 L-histidinol phosphate + H2O Salmonella enterica subsp. enterica serovar Typhimurium
-
 ?
-
 ?
3.1.3.15 L-histidinol phosphate + H2O Salmonella enterica subsp. enterica serovar Typhimurium TA387
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.15 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
3.1.3.15 Salmonella enterica subsp. enterica serovar Typhimurium TA387
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.15 L-histidinol phosphate + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium L-histidinol + phosphate
-
 ?
3.1.3.15 L-histidinol phosphate + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium TA387 L-histidinol + phosphate
-
 ?
3.1.3.15 L-histidinol phosphate + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
3.1.3.15 L-histidinol phosphate + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium TA387 ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.3.15 ? x * 16000-18000, SDS-PAGE Salmonella enterica subsp. enterica serovar Typhimurium

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.3.15 7.5
-
 in the absence of divalent metal ions Salmonella enterica subsp. enterica serovar Typhimurium