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Literature summary extracted from
- Crystalline fructose 1,6-bisposphatase from chicken breast muscle (1977), Arch. Biochem. Biophys., 183, 48-56.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.3.11 | citrate | activates | Gallus gallus |  |
| 3.1.3.11 | EDTA | activation | Gallus gallus | |
| 3.1.3.11 | His | activation | Gallus gallus | |
| 3.1.3.11 | NH4+ | activates | Gallus gallus | |
| 3.1.3.11 | NH4+ | at pH 7.4, in presence of 5 mM MgCl2, optimal activity at 40-50 mM | Gallus gallus | |
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 3.1.3.11 | - |
Gallus gallus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.3.11 | AMP | at pH 7.4, 0.0004 mM, complete inhibition | Gallus gallus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.1.3.11 | 0.0083 | - |
fructose 1,6-diphosphate | - |
Gallus gallus | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.3.11 | Mg2+ | divalent cation required. Mn2+ or Mg2+ | Gallus gallus | |
| 3.1.3.11 | Mn2+ | divalent cation required. Mn2+ or Mg2+ | Gallus gallus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.3.11 | 36000 | - |
4 * 36000, SDS-PAGE | Gallus gallus |
| 3.1.3.11 | 143800 | - |
muscle enzyme, equilibrium sedimentation | Gallus gallus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.3.11 | Gallus gallus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.3.11 | - |
Gallus gallus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.3.11 | muscle | breast muscle | Gallus gallus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.1.3.11 | 57 | - |
- |
Gallus gallus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.3.11 | D-fructose 1,6-diphosphate + H2O | - |
Gallus gallus | D-fructose 6-phosphate + phosphate | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.1.3.11 | tetramer | 4 * 36000, SDS-PAGE | Gallus gallus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.3.11 | 7.4 | 7.6 | in presence of EDTA or citrate | Gallus gallus |
| 3.1.3.11 | 8.2 | - |
in presence of Mn2+ or Mg2+ | Gallus gallus |
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Release 2023.1 (January 2023)
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