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Literature summary extracted from

  • Blaner W.S.; Prystowsky, J.H.; Smith, J.E.; Goodman, D.S.
    Rat liver retinyl palmitate hydrolase activity. Relationship to cholesteryl oleate and triolein hydrolase activities (1984), Biochim. Biophys. Acta, 794, 419-427.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.63 all-trans-retinyl bromoacetate 0.05 mM 50% inhibition Bos taurus
3.1.1.64 all-trans-retinyl bromoacetate 0.05 mM, 76% inhibition Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.63 0.66
-
 11-cis-retinyl palmitate
-
 Bos taurus
3.1.1.64 0.027
-
 all-trans-retinyl palmitate
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.63 microsome
-
 Bos taurus
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.63 Bos taurus
-
-
-
3.1.1.64 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.63 retinal pigment epithelium
-
 Bos taurus
-
3.1.1.64 retinal pigment epithelium
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.63 11-cis-retinyl palmitate + H2O
-
 Bos taurus 11-cis-retinol + palmitate
-
 ?
3.1.1.63 additional information also hydrolyzes all-trans-retinol with lower activity Bos taurus ?
-
 ?
3.1.1.64 all-trans-retinyl palmitate + H2O
-
 Bos taurus all-trans-retinol + palmitate
-
 ?
3.1.1.64 additional information also hydrolyzes 11-cis-retinyl palmitate with higher activity. The hydrolysis of all-trans-retinyl palmitate and 11-cis-retinyl palmitate may occur at distinct catalytic sites Bos taurus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.63 8 9
-
 Bos taurus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.1.1.63 0.05
-
 all-trans-retinyl bromoacetate
-
 Bos taurus