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Literature summary extracted from

  • Saheki, T.; Sase, M.; Nakano, K.; Azuma, F.; Katsunuma, T.
    Some properties of argininosuccinate synthetase purified from human liver and a comparison with the rat liver enzyme (1983), J. Biochem., 93, 1531-1537.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.3.4.5 0.019
-
 Asp reaction with 5 mM citrulline Homo sapiens
6.3.4.5 0.024
-
 citrulline reaction with 5 mM Asp Homo sapiens
6.3.4.5 0.042
-
 citrulline reaction with 0.5 mM Asp Homo sapiens
6.3.4.5 0.077
-
 ATP citrulline Homo sapiens
6.3.4.5 0.083
-
 Asp reaction with 0.5 mM citrulline Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.3.4.5 45000
-
 4 * 45000, SDS-PAGE Homo sapiens
6.3.4.5 185000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
6.3.4.5 Homo sapiens
-
-
-
6.3.4.5 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.3.4.5
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.3.4.5 1.3
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.4.5 ATP + citrulline + aspartate
-
 Homo sapiens AMP + diphosphate + 2-(Nomega-L-arginino)succinate
-
 ?
6.3.4.5 ATP + L-citrulline + L-Asp
-
 Homo sapiens AMP + diphosphate + L-argininosuccinate
-
 ?
6.3.4.5 ATP + L-citrulline + L-Asp
-
 Rattus norvegicus AMP + diphosphate + L-argininosuccinate
-
 ?

Subunits

EC Number Subunits Comment Organism
6.3.4.5 tetramer
-
 Rattus norvegicus
6.3.4.5 tetramer 4 * 45000, SDS-PAGE Homo sapiens