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Literature summary extracted from

  • Kimball, M.E.; Jacoby, L.B.
    Purification and properties of argininosuccinate synthetase from normal and canavanine-resistant human lymphoblasts (1980), Biochemistry, 19, 705-709.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.3.4.5 additional information
-
 additional information ATP: biphasic double-reciprocal plot Homo sapiens
6.3.4.5 0.061
-
 citrulline MGL8B2 enzyme Homo sapiens
6.3.4.5 0.078
-
 Asp MGL8B2 enzyme and MGL8D1 enzyme Homo sapiens
6.3.4.5 0.089
-
 citrulline MGL8D1 enzyme Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.3.4.5 45000
-
 4 * 45000, SDS-PAGE Homo sapiens
6.3.4.5 180000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
6.3.4.5 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.3.4.5
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.4.5 lymphoblast parental cell line MGL8B2 and canavanine-resistant cell line MGL8D1 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.3.4.5 0.95
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.4.5 ATP + citrulline + aspartate
-
 Homo sapiens AMP + diphosphate + 2-(Nomega-L-arginino)succinate
-
 ?
6.3.4.5 ATP + L-citrulline + L-Asp
-
 Homo sapiens AMP + diphosphate + L-argininosuccinate
-
 ?

Subunits

EC Number Subunits Comment Organism
6.3.4.5 tetramer 4 * 45000, SDS-PAGE Homo sapiens