EC Number | General Stability | Organism |
---|---|---|
6.3.4.5 | argininosuccinate stabilizes against heat treatment | Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.3.4.5 | 0.029 | - |
L-Asp | normal liver and from patients with citrullinemia | Homo sapiens | |
6.3.4.5 | 0.03 | - |
L-citrulline | normal liver | Homo sapiens | |
6.3.4.5 | 0.18 | - |
ATP | normal liver and from patients with citrullinemia | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
6.3.4.5 | 185000 | - |
sucrose density gradient centrifugation | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.3.4.5 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
6.3.4.5 | liver | normal and from patients with citrullinemia | Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.4.5 | ATP + L-citrulline + L-Asp | - |
Homo sapiens | AMP + diphosphate + L-argininosuccinate | - |
? |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
6.3.4.5 | additional information | - |
argininosuccinate stabilizes against heat treatment | Homo sapiens |
6.3.4.5 | 50 | - |
7 min, enzyme from normal liver and from patients with citrullinemia, in presence of 10 mM argininosuccinate, about 10% loss of activity | Homo sapiens |
6.3.4.5 | 50 | - |
7 min, enzyme from patients with citrullinemia, in absence of argininosuccinate, 95% loss of activity | Homo sapiens |
6.3.4.5 | 50 | - |
7 min, enzyme from normal liver, in absence of argininosuccinate, about 65% loss of activity | Homo sapiens |