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Literature summary extracted from

  • Rueffer, M.; Zenk, M.H.
    S-Adenosyl-L-methionine: (S)-7,8,13,14-tetrahydroberberine-cis-N-methyltransferase, a branch point enzyme in the biosynthesis of benzophenanthridine and protopine alkaloids (1986), Tetrahedron Lett., 27, 5603-5604.
No PubMed abstract available

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.1.1.122 72000
-
 gel filtration Corydalis vaginans

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.122 Berberis stenophylla
-
-
-
2.1.1.122 Corydalis vaginans
-
-
-
2.1.1.122 Fumaria officinalis
-
-
-
2.1.1.122 Lamprocapnos spectabilis
-
-
-
2.1.1.122 Papaver somniferum
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.122
-
 Corydalis vaginans

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.122 S-Adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine
-
 Papaver somniferum S-Adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine
-
 ?
2.1.1.122 S-Adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine
-
 Lamprocapnos spectabilis S-Adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine
-
 ?
2.1.1.122 S-Adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine
-
 Fumaria officinalis S-Adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine
-
 ?
2.1.1.122 S-Adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine
-
 Berberis stenophylla S-Adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine
-
 ?
2.1.1.122 S-Adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine
-
 Corydalis vaginans S-Adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine
-
 ?
2.1.1.122 S-Adenosyl-L-methionine + (S)-stylopine
-
 Papaver somniferum ?
-
 ?
2.1.1.122 S-Adenosyl-L-methionine + (S)-stylopine
-
 Lamprocapnos spectabilis ?
-
 ?
2.1.1.122 S-Adenosyl-L-methionine + (S)-stylopine
-
 Fumaria officinalis ?
-
 ?
2.1.1.122 S-Adenosyl-L-methionine + (S)-stylopine
-
 Berberis stenophylla ?
-
 ?
2.1.1.122 S-Adenosyl-L-methionine + (S)-stylopine at 77% of the activity with (S)-canadine Corydalis vaginans ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.1.1.122 8
-
-
 Corydalis vaginans