EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
6.3.4.16 | acetylglutamate | activates | Rattus norvegicus | |
6.3.4.16 | acetylglutamate | Km: 0.1 mM | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.3.4.16 | 2-Amino-4-oxo-5-chloropentanoic acid | - |
Rattus norvegicus | |
6.3.4.16 | Mn2+ | activates | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.3.4.16 | 1 | - |
ATP | MgATP2- | Rattus norvegicus | |
6.3.4.16 | 2 | - |
NH4+ | - |
Rattus norvegicus | |
6.3.4.16 | 5 | - |
HCO3- | - |
Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
6.3.4.16 | mitochondrion | - |
Rattus norvegicus | 5739 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
6.3.4.16 | Co2+ | activates | Rattus norvegicus | |
6.3.4.16 | Mg2+ | Mg2+ and Mn2+ are equally effective activators in the direction of carbamoyl phosphate synthesis, Km: 0.17 mM | Rattus norvegicus | |
6.3.4.16 | Mn2+ | Mg2+ and Mn2+ are equally effective activators in the direction of carbamoyl phosphate synthesis. Excess Mn2+ inhibits | Rattus norvegicus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
6.3.4.16 | 158000 | - |
1 * 158000, sedimentation equilibrium in 6 M guanidine hydrochloride containing DTT, predominantly exists in the monomeric form | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.3.4.16 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
6.3.4.16 | liver | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.4.16 | 2 ATP + NH4+ + HCO3- | - |
Rattus norvegicus | 2 ADP + phosphate + carbamoyl phosphate | - |
? | |
6.3.4.16 | 2 ATP + NH4+ + HCO3- | ATP in form of MnATP2- | Rattus norvegicus | 2 ADP + phosphate + carbamoyl phosphate | - |
? | |
6.3.4.16 | ATP + NH4+ + CO2 + H2O | no activity with Gln | Rattus norvegicus | ADP + phosphate + carbamoylphosphate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
6.3.4.16 | monomer | 1 * 158000, sedimentation equilibrium in 6 M guanidine hydrochloride containing DTT, predominantly exists in the monomeric form | Rattus norvegicus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
6.3.4.16 | 6.8 | 7.6 | - |
Rattus norvegicus |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
6.3.4.16 | 6.3 | 8 | 50% of maximal activity at pH 6.3 and 8.0 | Rattus norvegicus |