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Literature summary extracted from

  • Rao, P.V.; Zigler, J.S.
    Purification and characterization of zeta-crystallin/quinone reductase from guinea pig liver (1992), Biochim. Biophys. Acta, 1117, 315-320.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.6.5.5 35000
-
 4 * 35000, SDS-PAGE Cavia porcellus
1.6.5.5 140000
-
 gel filtration Cavia porcellus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.6.5.5 additional information Cavia porcellus although in the lens the enzyme is considered to be a crystallin, or lens structural protein, because of its high abundance its enzymatic activity and expression at catalytic levels in other tissues of various species suggest that it has a fundamental physiological role outside the lens, perhaps in the detoxification of xenobiotics ?
-
 ?
1.6.5.5 additional information Homo sapiens although in the lens the enzyme is considered to be a crystallin, or lens structural protein, because of its high abundance its enzymatic activity and expression at catalytic levels in other tissues of various species suggest that it has a fundamental physiological role outside the lens, perhaps in the detoxification of xenobiotics ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.6.5.5 Cavia porcellus
-
-
-
1.6.5.5 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.6.5.5
-
 Cavia porcellus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.6.5.5 liver
-
 Cavia porcellus
-
1.6.5.5 liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.6.5.5 6
-
-
 Cavia porcellus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.6.5.5 1,2-naphthoquinone + NADPH
-
 Cavia porcellus 1,2-naphthoquinol + NADP+
-
 ?
1.6.5.5 5-hydroxy-1,4-naphthoquinone + NADPH
-
 Cavia porcellus 5-hydroxy-1,4-naphthosemiquinone + NADP+
-
 ?
1.6.5.5 9,10-phenanthrenequinone + NADPH
-
 Cavia porcellus 9,10-phenanthrenesemiquinone + NADP+
-
 ?
1.6.5.5 additional information although in the lens the enzyme is considered to be a crystallin, or lens structural protein, because of its high abundance its enzymatic activity and expression at catalytic levels in other tissues of various species suggest that it has a fundamental physiological role outside the lens, perhaps in the detoxification of xenobiotics Cavia porcellus ?
-
 ?
1.6.5.5 additional information although in the lens the enzyme is considered to be a crystallin, or lens structural protein, because of its high abundance its enzymatic activity and expression at catalytic levels in other tissues of various species suggest that it has a fundamental physiological role outside the lens, perhaps in the detoxification of xenobiotics Homo sapiens ?
-
 ?
1.6.5.5 NADPH + H+ + oxidized 2,6-dichlorophenolindophenol
-
 Cavia porcellus NADP+ + reduced 2,6-dichlorophenolindophenol
-
 ?

Subunits

EC Number Subunits Comment Organism
1.6.5.5 tetramer 4 * 35000, SDS-PAGE Cavia porcellus