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Literature summary extracted from
- Camel lens zeta-crystallin kinetics and its inhibition by dicoumarol (1996), Biochem. Mol. Biol. Int., 38, 251-258.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.6.5.5 | dicoumarol | competitive with respect to 2,6-dichlorophenol-indophenol, uncompetitive with respect to NADPH | Camelus dromedarius |  |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.6.5.5 | 0.007 | - |
NADPH | - |
Camelus dromedarius | |
| 1.6.5.5 | 0.0153 | - |
oxidized 2,6-dichlorophenolindophenol | - |
Camelus dromedarius | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.6.5.5 | Camelus dromedarius | - |
camel | - |
Reaction
| EC Number | Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|---|
| 1.6.5.5 | NADPH + H+ + 2 quinone = NADP+ + 2 semiquinone | reaction with 2,6-dichlorophenolindophenol and NADPH proceeds through a ping-pong mechanism | Camelus dromedarius |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.6.5.5 | lens | - |
Camelus dromedarius | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.6.5.5 | NADPH + H+ + oxidized 2,6-dichlorophenolindophenol | - |
Camelus dromedarius | NADP+ + reduced 2,6-dichlorophenolindophenol | - |
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