BRENDA - Enzyme Database show

Isolation and characterization of mutations in the human holocarboxylase synthetase cDNA

Suzuki, Y.; Aoki, Y.; Ichida, Y.; Chiba, A.; Iwamatsu, T.; Kishini, T.; Matsubara, Y.; Narisawa, K.; Nature Genet. 8, 122-128 (1994)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
6.3.4.10
-
Homo sapiens
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
6.3.4.10
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
eukaryota
plays an essential role in biotin utilization
?
-
-
-
6.3.4.10
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
Homo sapiens
its deficiency causes biotin-responsive multiple carboxylase deficiency in humans
?
-
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
6.3.4.10
eukaryota
-
-
-
6.3.4.10
Homo sapiens
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6.3.4.10
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1393
eukaryota
AMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1393
eukaryota
-
6.3.4.10
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1393
Homo sapiens
AMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1393
Homo sapiens
-
6.3.4.10
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
plays an essential role in biotin utilization
1393
eukaryota
?
-
-
-
-
6.3.4.10
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
its deficiency causes biotin-responsive multiple carboxylase deficiency in humans
1393
Homo sapiens
?
-
-
-
-
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
6.3.4.10
-
Homo sapiens
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
6.3.4.10
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
eukaryota
plays an essential role in biotin utilization
?
-
-
-
6.3.4.10
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
Homo sapiens
its deficiency causes biotin-responsive multiple carboxylase deficiency in humans
?
-
-
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6.3.4.10
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1393
eukaryota
AMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1393
eukaryota
-
6.3.4.10
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1393
Homo sapiens
AMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1393
Homo sapiens
-
6.3.4.10
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
plays an essential role in biotin utilization
1393
eukaryota
?
-
-
-
-
6.3.4.10
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
its deficiency causes biotin-responsive multiple carboxylase deficiency in humans
1393
Homo sapiens
?
-
-
-
-