BRENDA - Enzyme Database show

In vitro synthesis of propionyl-CoA holocarboxylase by a partially purified mitochondrial preparation from biotin-deficient chicken liver

Murthy, P.N.A.; Mistry, S.P.; Can. J. Biochem. 52, 800-803 (1974)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
6.3.4.10
ADP
-
Gallus gallus
6.3.4.10
AMP
-
Gallus gallus
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
6.3.4.10
0.0033
-
biotin
-
Gallus gallus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
6.3.4.10
cytosol
-
Gallus gallus
5829
-
6.3.4.10
mitochondrion
-
Gallus gallus
5739
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
6.3.4.10
Gallus gallus
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
6.3.4.10
-
Gallus gallus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
6.3.4.10
liver
-
Gallus gallus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6.3.4.10
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1389
Gallus gallus
AMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1389
Gallus gallus
-
6.3.4.10
CTP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
28% of the activity relative to ATP
1389
Gallus gallus
CMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
-
-
-
6.3.4.10
GTP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1389
Gallus gallus
GMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
-
-
-
6.3.4.10
ITP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1389
Gallus gallus
IMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
-
-
-
6.3.4.10
UTP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
95% of the activity relative to ATP
1389
Gallus gallus
UMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
-
-
-
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.3.4.10
8
-
-
Gallus gallus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
6.3.4.10
ADP
-
Gallus gallus
6.3.4.10
AMP
-
Gallus gallus
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
6.3.4.10
0.0033
-
biotin
-
Gallus gallus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
6.3.4.10
cytosol
-
Gallus gallus
5829
-
6.3.4.10
mitochondrion
-
Gallus gallus
5739
-
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
6.3.4.10
-
Gallus gallus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
6.3.4.10
liver
-
Gallus gallus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6.3.4.10
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1389
Gallus gallus
AMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1389
Gallus gallus
-
6.3.4.10
CTP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
28% of the activity relative to ATP
1389
Gallus gallus
CMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
-
-
-
6.3.4.10
GTP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1389
Gallus gallus
GMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
-
-
-
6.3.4.10
ITP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
1389
Gallus gallus
IMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
-
-
-
6.3.4.10
UTP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
95% of the activity relative to ATP
1389
Gallus gallus
UMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
-
-
-
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.3.4.10
8
-
-
Gallus gallus