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Literature summary extracted from

  • Moore, J.D.; Coggins, J.R.; Virden, R.; Hawkins, A.R.
    Efficient independent activity of a monomeric, monofunctional dehydroquinate synthase derived from the N-terminus of the pentafunctional AROM protein of Aspergillus nidulans (1994), Biochem. J., 301, 297-304.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.3.4 diethyl dicarbonate
-
 Aspergillus nidulans
4.2.3.4 EDTA
-
 Aspergillus nidulans

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.2.3.4 0.0022
-
 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate
-
 Aspergillus nidulans
4.2.3.4 0.003
-
 NAD+ cofactor NAD+ Aspergillus nidulans

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.2.3.4 Zn2+
-
 Aspergillus nidulans

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.2.3.4 43000
-
 gel filtration Aspergillus nidulans

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.4 Aspergillus nidulans
-
 overview
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.3.4
-
 Aspergillus nidulans

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.2.3.4 14.9
-
-
 Aspergillus nidulans

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.3.4 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate
-
 Aspergillus nidulans 3-dehydroquinate + phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
4.2.3.4 monomer 1 * 43000, gel filtration Aspergillus nidulans

Cofactor

EC Number Cofactor Comment Organism Structure
4.2.3.4 NAD+
-
 Aspergillus nidulans