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Literature summary extracted from

  • Pinto, J.T.; Suffoletto, B.P.; Berzin, T.M.; Qiao, C.H.; Lin, S.; Tong, W.P.; May, F.; Mukherjee, B.; Heston, W.D.W.
    Prostate-specific membrane antigen: a novel folate hydrolase in human prostatic carcinoma cells (1996), Clin. Cancer Res., 2, 1445-1451.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.17.21
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.21 Homo sapiens
-
 male
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.17.21 prostate gland prostrate carcinoma cell line LNCaP Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.21 methotrexate triglutamate + H2O
-
 Homo sapiens L-Glu + methotrexate
-
 ?
3.4.17.21 N-Acetyl-L-Asp-L-Glu + H2O
-
 Homo sapiens N-Acetyl-L-Asp + L-Glu
-
 ?
3.4.17.21 pteroylpentaglutamate + H2O
-
 Homo sapiens L-Glu + pteroylglutamate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.17.21 5
-
 second optimum at pH 8 Homo sapiens
3.4.17.21 8
-
 second optimum at pH 5 Homo sapiens