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Literature summary extracted from

  • Hirst, M.; Haliday, E.; Nakamura, J.; Lou, L.
    Human GMP synthetase. Protein purification, cloning, and functional expression of cDNA (1994), J. Biol. Chem., 269, 23830-23837.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.5.2 expression in Escherichia coli Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.3.5.2 76725
-
 x * 76725, calculation from nucleotide sequence Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.5.2 additional information Homo sapiens key enzyme in the de novo synthesis of guanine nucleotides ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.5.2 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.3.5.2
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.5.2 A3 cell A3.01 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.3.5.2 2.8
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.5.2 ATP + XMP + NH4+
-
 Homo sapiens AMP + diphosphate + GMP
-
 ?
6.3.5.2 additional information no substrates mentioned Homo sapiens ?
-
 ?
6.3.5.2 additional information key enzyme in the de novo synthesis of guanine nucleotides Homo sapiens ?
-
 ?

Subunits

EC Number Subunits Comment Organism
6.3.5.2 ? x * 76725, calculation from nucleotide sequence Homo sapiens