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Literature summary extracted from

  • Vasseur, M.; Van Melle, G.; Frangne, R.; Alvarado, F.
    Alkali-metal-ion- and H+-dependent activation and/or inhibition of intestinal brush-border sucrase. A model involving three functionally distinct key prototropic groups (1988), Biochem. J., 251, 667-675.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.48 H+ competitive inhibitor in the interaction of sucrase with sucrose and sodium Oryctolagus cuniculus
3.2.1.48 Li+ high concentration, 300 mM Li+, pH dependent inhibition, complete at pH 8 Oryctolagus cuniculus
3.2.1.48 Na+ high concentration Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.48 22
-
 sucrose value remains constant at Li+ concentration from 20-120 mM Oryctolagus cuniculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.2.1.48 Li+ low concentration: activation Oryctolagus cuniculus
3.2.1.48 Na+ low concentration: activation Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.48 maltose + H2O Oryctolagus cuniculus
-
 2 glucose
-
 ?
3.2.1.48 sucrose + H2O Oryctolagus cuniculus
-
 D-glucose + D-fructose
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.48 Oryctolagus cuniculus
-
 rabbit
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.48 maltose + H2O
-
 Oryctolagus cuniculus 2 glucose
-
 ?
3.2.1.48 sucrose + H2O
-
 Oryctolagus cuniculus D-glucose + D-fructose
-
 ?